- Wide receiver Sammy Watkins (58), wide receiver Robert Woods (52) and running back Fred Jackson (53) all have at least 50 receptions this season. 2014 marks the seventh time in team history and first time since 2003 (Eric Moulds, Josh Reed and Bobby Shaw), that three Bills posted 50-catch campaigns.
- With his 127 receiving yards, Watkins is now the first Bills rookie to produce four 100-yard games in a season. He is the first Bill to go over the century mark four times in a season overall since Lee Evans in 2008.
- The Bills have produced six 100-yard receiving games in 2014 (four from Watkins, one from Scott Chandler and one from Robert Woods) – the most in a season for a Bills team since 11, 100-yard games in 2002.
- With 822 yards receiving, Watkins is among three current rookies with 800 or more yards (Mike Evans – 935; Kelvin Benjamin-848).
- Jackson became the fifth Bill to accumulate 8,000 yards from scrimmage, joining Thurman Thomas, Andre Reed, O.J. Simpson and Eric Moulds.
- Jackson is also one of two Bills running backs (Thurman Thomas) with 5,000 yards rushing and 2.500 yards receiving, and one of just six active running backs to accomplish the feat (Steven Jacskon, Frank Gore, Maurice Jones-Drew, Matt Forte and Reggie Bush).
- Cornerback Corey Graham became the first Bill to record both an interception and fumble recovery in the same game since Jairus Byrd vs. Miami on Nov. 15, 2012.
- The Bills still lead the NFL with 48 sacks, but were held without a sack for the first time in the 2014 season.
- The Buffalo defense held Broncos QB Peyton Manning without a touchdown pass, breaking a streak of 51 consecutive games in which Manning had tossed a score. His streak was the third longest in the NFL.
- The Bills are the only NFL franchise to hold Peyton Manning under 175 yards passing and without a passing touchdown in three separate games.
- Kyle Orton totaled 355 yards passing and is now the 10th Bills quarterback in team history with at least two 300-yard passing games in a season, and the first since Ryan Fitzpatrick in 2012.
- Orton set a team record with 57 pass attempts and tied a team record with 38 completions (Joe Ferguson Oct. 9, 1983 vs. Miami).
