Top Storylines

A Bills-Chiefs playoff rematch, injury update, the key to slowing Patrick Mahomes + more.

Injury updates, Buffalo's playoff numbers at home, slowing an explosive Steelers offense + more.

The road to the playoffs, Josh Allen's numbers against Miami, why the defense is on a heater + more.

Playoff picture and division chances, revenge against NE, James Cook and Co against one of the best run defenses + more.

Beware of interim head coaches, shutting down another elite pass rusher, a look at the playoff picture + more.

Playoff implications, a big test for Buffalo's offensive line, going for three straight against Dallas + more.

An important game with playoff implications, can McDermott stay perfect off the bye, the winning formula to beating KC's offense + more

Bills begin their toughest stretch, McDermott's first game in Philly as a HC, first meeting between Allen and Hurts + more.

A look at Bills new play caller Joe Brady, an important stretch ahead, why the Jets D is tough to score against + more.

Can the Bills get back to their high scoring ways, keeping a winning record at home, Josh Allen on Monday night + more.

A playoff rematch, a big test for Buffalo's DBs, Bills looking to stay undefeated on SNF + more.

Looking to stay undefeated vs. NFC, Josh Allen has this record on TNF, getting it right in the first half + more.

Another top 10 test for Buffalo's offense, going for five-straight against New England, say goodbye to 1PM games + more.

Brian Daboll's return, filling the void of more injuries, Daniel Jones' status + more.

London logistics, the offense's hot start, a void without Tre'Davious White + more.

A rivalry renewed, slowing the Dolphins offense, Josh Allen vs. Miami at home + more. 

A sold-out FedEx Field is expected for Sunday's matchup. These important storylines are worth monitoring this week. 

Bouncing back after a Week 1 loss, getting ready for another explosive rushing attack, a new-look Raiders offense + more.

Josh Allen on a MNF stage, Aaron Rodgers vs. Buffalo, Damar Hamlin's return + more.

The race to first place, two of the NFL's hottest teams, Josh Allen vs. a former teammate and more.

The perfect Christmas gift, Josh Allen facing the Bears for the first time, Buffalo's December win streak, Leslie Frazier heading home and more.

A rematch vs. Miami, the state of the AFC East, from one weather extreme to another, defensive line consistency and more.

The AFC playoff picture, a new QB for the Jets, back at home after three weeks on the road and more.

The division gauntlet begins, Buffalo's success over New England, why multiple weapons are needed for Thursday, injury update and more.

How Josh Allen has been great on Thanksgiving, back-to-back games at Ford Field, another test at stopping the run, Detroit's win streak and more.

How the Bills can learn from their mistakes, why the turnover battle is so important, how to stop Nick Chubb a health update and more.

Stefon Diggs set to face former team, James Cook vs. Dalvin Cook, stopping the run and more to know for Sunday's game.

Josh Allen's career stats vs. Jets, two top 10 defenses, WRs going up against Sauce Gardner and more.

The Bills are back on primetime this week. These six factors will have a lot to do with how this matchup plays out.

Moving on from :13 seconds, two of the best QBs facing off & a new look Chiefs WR corps 

Kenny Pickett's first NFL start and who on the Bills has familiarity with him, how the injury bug has hit both teams and more.

Josh Allen and Lamar Jackson lead dynamic offenses, injury updates, a great third down offense and more.

A divisional matchup featuring two undefeated teams, the NFL's best wide receivers on display, a homecoming for several Bills, injury watch and much more.

A home opener on a primetime stage, facing another good pass rush, stopping Derrick Henry and more.

Taking on the defending Super Bowl champs, Von Miller going up against his former team, Josh Allen's first game in California + more.

Plenty of history between the Bills and Chiefs, Allen-Mahomes the NFL's top QB rivalry? Will Sunday will be the toughest game yet for Buffalo's secondary + more.

Playoff history vs. the Patriots, why the Bills and Patriots were opposites to end the regular season, the defense's monstrous end to the season, weather report + more.

Division title on the line, a chance to sweep the Jets again, Devin Singletary's hot stretch, milestones to watch for and more.

Playoff chances, Josh Allen's streak, Bills WR options, two playmakers the Bills need to stop and more.

The rematch, why red zone execution is so important, how Covid-19 could affect who's available and more.

Two teams desperate for wins, why Carolina's defense is one of the best, the potential to face two quarterbacks and more.

Strength vs strength, attacking through the air, and facing Tom Brady

A battle for first place in the AFC East, two of the best defenses, two different offenses, a big stage on MNF and more.

A fight to stay alive in the playoff race, another opportunity to stop the run, the Thanksgiving stage, plus more storylines to follow.

A playoff rematch, Bills offense back on track, stopping Jonathan Taylor and more.

Turning a loss into a learning opportunity, preparing for multiple Jets quarterbacks, offensive line health and a look at the AFC East standings.

How Sean McDermott fares against rookie quarterbacks, how the Bills have been dominant in this category, an offensive line that could continue its shuffling and more.

Buffalo's dominance over Miami, Josh Allen's 50th career start, Miami's tough streak, Sean McDermott undefeated following a bye and more.

How Buffalo has fared against Tennessee in recent history, taking down Derrick Henry, primetime Josh Allen and more.

How an AFC Championship loss led the Bills to change, how to limit Patrick Mahomes and his weapons, why it's important to respect Kansas City's defense and more.

Can the Bills handle business as a heavy favorite, another young quarterback comes to town, will the offense continue its hot streak - here's what to watch for this week.

A head coaching reunion, a team record on the horizon for Josh Allen, former Bills return to Orchard Park plus more to follow in this week's Bills vs. Washington matchup.

Buffalo's recent success against Miami, the Bills offense is ready to bounce back, Tua in year 2 and more.

The last two matchups against Pittsburgh, Josh Allen vs. Ben Roethlisberger, a new OC in Pittsburgh and more.

To play or rest, Miami's playoff hopes, a shot at FitzMagic and more in this week's top storylines.

Sights set on a No. 2 seed, more records to break, a chance to sweep the Patriots and more in this week's top storylines.

One win away from claiming the AFC East, can the defense continue their takeaway streak, Stefon Diggs close to breaking more records and more in this week's top storylines.

A game that matters for both teams, a Steelers team that's on their third game in 11 days, the Bills explosive offense could be the perfect match for a talented Steelers defense and more in this week's top storylines.

Another chance at State Farm Stadium, an opportunity for the first Bills MNF win this century, a look at two talented coordinators and more in this week's top storylines to know.

Sean McDermott is undefeated following a bye, another tough test for the secondary, a chance to turn the run game around and more in this week's top storylines.