The Bills opened up a pair of roster spots Tuesday placing CB Ron Brooks and TE Charles Clay to injured reserve.
Clay has missed the last two games with a back injury suffered in Week 14 at Philadelphia. He finished his first season with the Bills with 51 catches for 528 yards and three touchdowns.
Brooks served mainly as a primary gunner on special teams and had just returned to the lineup last week from a shoulder/neck injury that forced him to go through the concussion protocol. No word on whether his I-R designation was prompted by a new injury or a recurrence of the original injury.
With Brooks and Clay moved to injured reserve the Bills will presumably have to fill the vacant roster spots with players at the same position.
Buffalo is down to two healthy tight ends in Chris Gragg and Nick O'Leary.
They also have just three healthy corners with Nickell Robey, Mario Butler and Leodis McKelvin ready to go this week. Ronald Darby is a question mark after missing last week's game with a groin injury.
This week's opponent the New York Jets run four wides as their most popular offensive formation. Corners and tight ends who are potential options on the team's practice squad include CBs Merril Noel and Sammy Seamster and TEs Blake Annen and Jacob Maxwell.