They were questionable coming into today's game, but the Bills will be without two of their veteran safeties in Rafael Bush and Micah Hyde for their matchup with the Titans.
Bush and Hyde were unable to practice at all this week due to shoulder and groin injuries respectively.
It leaves Buffalo with Jordan Poyer, Siran Neal and Dean Marlowe as the team's only healthy safeties for today's game. Marlowe was called up from the team's practice squad on Saturday.
Here's the full list of Bills inactives.
S Rafael Bush
S Micah Hyde
CB Dontae Johnson
RB Marcus Murphy
OL Wyatt Teller
OL Conor McDermott
OL Ike Boettger