10. On the road again

For the second consecutive week, the Bills will be playing away from New Era Field. Venturing west to Kansas City, Buffalo is looking to return home with a much-needed 'W.' The game will signify the end of Buffalo's road trips until Week 16 when the team travels to New England.

9. White on Blue

As they take on the Chiefs, the Bills will be decked out in a white on blue uniform combo. Take a look:

8. Final dose of AFC West action

Despite losing to the Los Angeles Chargers Week 11, the Bills have made their mark on the AFC West this year. With wins against both the Denver Broncos and Oakland Raiders, Buffalo is aiming to finish strong. The Chiefs, who have lost four of their last five games, still hold the top spot in the division.  

7. Return of the run game

After a slow start, Buffalo's run game has recently taken on new life. With feature back LeSean McCoy paving the way, the offense has been able to make positive strides on the ground. Combined with newcomer Travaris Cadet, who showed promise last week, the Bills' run attack should perform well against a lackluster Kansas City run 'D.'

6. A friendly face-off

Although Sunday will mark Sean McDermott's first visit to Arrowhead Stadium since he was named Buffalo's head coach, he's certainly no stranger to Andy Reid and company. Having spent the bulk of his NFL coaching career with the Eagles, McDermott considers Reid one of his closest mentors.

5. Hauschka looking to cash in

During his short stint with the Bills, veteran kicker Stephen Hauschka has proven more than reliable in long distance situations. The specialist is six-for-six on field goal attempts from 50 yards or more this season. Having made 13 straight from that range, Hauschka now holds the NFL record. Working to keep his streak alive, Hausch-money may get to cash in a few more against the Chiefs.

4.T2 back under center

Bills quarterback Tyrod Taylor is back in command and will look to lead his team to a Week 12 victory. Striving to capitalize on each drive, Taylor will make use of his arm and legs to move the chains. The dual threat signal caller needs one rushing touchdown and one passing to join Cam Newtown and Kirk Cousins as the only quarterbacks to achieve the feat in 10 games since 2015.

3. Defense down, not out

Buffalo's once dominant defense, has struggled in a few critical areas over the past few weeks. Chief among them is their ability to stop the run and prevent big plays. Confident that they can stay focused and make the necessary corrections to revert to prior form, the unit is working together to get the job done. 

"We have some real good leaders; Kyle Williams being one of those guys, Lorenzo Alexander being another," said defensive coordinator Leslie Frazier. "Talked to Lorenzo a little bit after the game, and Kyle some after the game as well; the big thing for us...Is really focusing on the Kansas City Chiefs. That's the most important game of our season because it's the next game in our season."

2. McCoy chasing more than 10k

With only 337 yards to go, LeSean McCoy is well on his way to achieving his goal of 10,000 yards rushing. However, the milestone is not the only one within his grasp. Playing in his 38th Bills game on Sunday, the elite ball carrier needs just 129 yards to move ahead of Travis Henry and become the fastest Bills running back to reach the 3,000-yard mark. McCoy could also move into 10th place on the team's all-time rushing list by picking up 62 yards.

1. No time like the present

With the Bills still in the thick of the playoff race, the team knows they need to take care of business against the Chiefs. Getting the victory at Arrowhead Stadium would not only get the Bills back on track, it would give them a boost in the conference.