| 2010-09-01 | Bills Focus: Lions Preseason Preview |
| 2010-09-02 | Evans reception |
| 2010-09-02 | Florence INT |
| 2010-09-02 | Lions 28, Bills 23 |
| 2010-09-02 | Chan Gailey Postgame Press Conference |
| 2010-09-02 | Levi Brown Postgame Press Conference |
| 2010-09-02 | Brian Brohm Postgame Press Conference |
| 2010-09-02 | Bills Roundup: Buffalo Loses Preseason Finale |
| 2010-09-04 | Jairus Byrd on Returning to Practice |
| 2010-09-04 | Chan Gailey on Cutdown Day Decisions |
| 2010-09-04 | Players React to Cutdown Day |
| 2010-09-05 | 2010 Bills Preseason Highlights |
| 2010-09-06 | Chan Gailey Monday Update |
| 2010-09-06 | Trent Edwards Meets the Media |
| 2010-09-06 | Bills Roundup: Two Players Sign; Injury Updates |
| 2010-09-08 | Chan Gailey Wednesday Press Conference |
| 2010-09-08 | Trent Edwards Wednesday Press Conference |
| 2010-09-08 | C.J. Spiller Wednesday Press Conference |
| 2010-09-08 | Bills Roundup: Spiller Named Week 1 Starter |
| 2010-09-09 | Chan Gailey Thursday Update |
| 2010-09-09 | Bills Focus: The Marshall Plan |
| 2010-09-10 | Back to Football Friday Press Conference |
| 2010-09-10 | Akin Ayodele Meets with the Media |
| 2010-09-10 | "What's the Word" with George Wilson |
| 2010-09-11 | Dolphins Game Preview with Chan Gailey |
| 2010-09-11 | Week 1: Dolphins vs. Bills Preview |
| 2010-09-11 | Playbook: Dolphins vs. Bills |
| 2010-09-12 | Week 1: Dolphins Game Preview |
| 2010-09-12 | Week 1: Film Session: Buffalo's Offense |
| 2010-09-12 | Week 1: Player Guest Donte Whitner |
| 2010-09-12 | Week 1: Season Preview |
| 2010-09-12 | Week 1: Final Thoughts |
| 2010-09-12 | Week 1: Dolphins Game Plan |
| 2010-09-12 | Week 1: Question of the Week |
| 2010-09-12 | Week 1: Two Minute Drill |
| 2010-09-12 | Week 1: Tops Tailgreats Cook-off |
| 2010-09-12 | Week 1: Tasker's Take and Open Mic |
| 2010-09-12 | Parrish TD rec |
| 2010-09-12 | Dolphins vs. Bills highlights |
| 2010-09-12 | Chan Gailey Postgame Press Conference |
| 2010-09-12 | Trent Edwards Postgame Press Conference |
| 2010-09-12 | Bills Roundup: Offense Struggles in Opener |
| 2010-09-13 | Buddy Nix Speaks at the Monday QB Club |
| 2010-09-13 | Chan Gailey Monday Press Conference |
| 2010-09-15 | Chan Gailey Wednesday Press Conference |
| 2010-09-15 | Trent Edwards Wednesday Press Conference |
| 2010-09-15 | Bills Roundup: LB Playing Time; Team Preps for GB |
| 2010-09-16 | Week 2: Bills vs. Packers Preview |
| 2010-09-16 | Bills Focus: Getting Pressure on Rodgers |
| 2010-09-17 | "What's the Word" with George Wilson |
| 2010-09-18 | Bills Focus: 1-on-1 with Chan Gailey |
| 2010-09-19 | Week 2: Packers Game Plan |
| 2010-09-19 | Week 2: Question of the Week |
| 2010-09-19 | Week 2: Tasker's Take and Open Mic |
| 2010-09-19 | Week 2: Two Minute Drill |
| 2010-09-19 | Tops Tailgreat Cook-off |
| 2010-09-19 | Week 2: Packers Game Preview |
| 2010-09-19 | Week 2: Game Recap |
| 2010-09-19 | Week 2: Film Session-Packers Offense |
| 2010-09-19 | Week 2: Final Thoughts |
| 2010-09-19 | Week 2: Player Guest Steve Johnson |
| 2010-09-19 | Fred Jackson 3-yard TD |
| 2010-09-19 | Bills vs. Packers highlights |
| 2010-09-19 | Chan Gailey Postgame Press Conference |
| 2010-09-19 | Trent Edwards Postgame Press Conference |
| 2010-09-19 | Bills Roundup: Big Second Half Propels Pack |
| 2010-09-20 | Chan Gailey Names Fitzpatrick Starter |
| 2010-09-20 | Ryan Fitzpatrick on Being Named Starter |
| 2010-09-20 | Bills Roundup: Fitzpatrick Named Starter |
| 2010-09-22 | Chan Gailey Wednesday Press Conference |
| 2010-09-22 | Ryan Fitzpatrick Wednesday Press Conference |
| 2010-09-22 | Bills Roundup: Fitzpatrick Takes the Reins |
| 2010-09-23 | Week 3: Bills vs. Patriots Preview |
| 2010-09-23 | Bills Focus: The Moss/Welker Combo |
| 2010-09-24 | "What's the Word" with George Wilson |
| 2010-09-25 | Bills Focus: Patriots Preview with Chan Gailey |
| 2010-09-26 | Week 3: Tasker's Take and Open Mic |
| 2010-09-26 | Week 3: Question of the Week |
| 2010-09-26 | Week 3: Tops Tailgreat Cook-off |
| 2010-09-26 | Week 3: Two Minute Drill |
| 2010-09-26 | Week 3: Patriots Game Plan |
| 2010-09-26 | Week 3: Final Thoughts |
| 2010-09-26 | Week 3: Film Session - Stopping New England |
| 2010-09-26 | Week 3: Patriots Game Preview |
| 2010-09-26 | Week 3: Packers Game Recap |
| 2010-09-26 | Week 3: Player Guest Marcus Stroud |
| 2010-09-26 | Bills fumble recovery |
| 2010-09-26 | Spiller's first touchdown |
| 2010-09-26 | WK 3 Can't-Miss Play: Spiller thriller |
| 2010-09-26 | Fitzpatrick 37-yard TD pass |
| 2010-09-26 | Bills vs. Patriots highlights |
| 2010-09-26 | Chan Gailey Postgame Press Conference |
| 2010-09-26 | Ryan Fitzpatrick Postgame Press Conference |
| 2010-09-26 | C.J. Spiller Postgame Press Conference |
| 2010-09-26 | Bills Roundup: Improved Offense Not Enough vs Pats |
| 2010-09-27 | Chan Gailey on Releasing Trent Edwards |
| 2010-09-27 | Ryan Fitzpatrick on Release of Trent Edwards |
| 2010-09-27 | Bills Roundup: Reaction to Edwards Release |
| 2010-09-29 | Chan Gailey Wednesday Press Conference |
| 2010-09-29 | Ryan Fitzpatrick Wednesday Press Conference |
| 2010-09-29 | Bills Roundup: Poz Returns; Stroud, Davis Sit Out |
| 2010-09-30 | Week 4: Jets vs. Bills Preview |
| 2010-09-30 | Gailey: Stroud and Davis Out for Sunday |
| 2010-09-30 | Bills Focus: Containing Dustin Keller |
| 2010-09-30 | Welcome Video 2011 |
