Isaiah McKenzie catches for a 23-yard touchdown from Josh Allen | Bills at 49ers

See how the Bills hit the practice field as they look to get a win down in South Florida vs the Miami Dolphins.

The Steelers defeated the Bills 23-16 in the season opener from Highmark Stadium in Orchard Park, N.Y.

Buffalo Bills running back Devin Singletary slices through Steelers defense for 25-yard burst.

Josh Allen finds Gabriel Davis in the back of the end zone for Buffalo's first touchdown of 2021.

Buffalo Bills quarterback Josh Allen rips 37-yard fastball to wide receiver Gabriel Davis on third down.

Buffalo Bills wide receiver Emmanuel Sanders lays out for a spectacular sideline grab.

Buffalo Bills wide receiver Isaiah McKenzie hits turbo for electric 75-yard kick return to start season.

Dawson Knox recalls his "Bills Mafia Moment" from the AFC Wild Card game as he anticipates welcoming fans back to Highmark Stadium for the 2021 home opener. One Sunday Closer is presented by Game Day Vodka.

Watch Buffalo Bills quarterback Josh Allen's best plays vs. Packers | Preseason Week 3

Watch the Buffalo Bills' best defensive plays from the 2021 Preseason Week 3 matchup against the Green Bay Packers.

The Bills defeated the Packers 19-0 in their preseason finale at Highmark Stadium.

Buffalo Bills rookie defensive end Boogie Basham stuffs Green Bay Packers running back Dexter Williams for a fourth-down stop.

Buffalo Bills quarterback Jake Fromm's powerful run results in 13-yard rushing TD.

Bills running back Zack Moss scored the game's second touchdown on a three-yard reception.

Buffalo Bills quarterback Josh Allen sprints left, throws right to wide receiver Cole Beasley for 21-yards.

Micah Hyde picked off Packers quarterback Jordan Love in the end zone.

Buffalo Bills wide receiver Gabriel Davis swipes past Green Bay Packers cornerback Kabion Ento on a 22-yard catch and run.

Buffalo Bills cornerback Tre'Davious White stops the Green Bay Packers with a pass breakup on fourth down.

Josh Allen threw his first touchdown of the preseason to Gabriel Davis.

Watch some of Buffalo Bills quarterback Mitchell Trubisky's best plays against the Chicago Bears in Preseason Week 2.

Watch the highlights as the Bills defeated the Bears 41-15 in the week two of the preseason.

Buffalo Bills wide receiver Marquez Stevenson reverses field for 79-yard punt-return TD.

Buffalo Bills quarterback Mitchell Trubisky completes a 16-yard pass to wide receiver Jake Kumerow.

Buffalo Bills cornerback Nick McCloud intercepts a pass from Chicago Bears quarterback Andy Dalton.

Buffalo Bills quarterback Mitchell Trubisky completes a 26-yard to tight end Jacob Hollister.