James Cook's best plays from 117-yard game vs. Saints Week 4

Watch the best plays from Buffalo Bills running back James Cook during Week 4 of the 2025 NFL season against the New Orleans Saints. Cook totaled 117 total yards and a rushing touchdown.

Watch highlights from the matchup between the New Orleans Saints and the Buffalo Bills during Week 4 of the 2025 NFL season.

Highlights from the Week 4 matchup between the New Orleans Saints and the Buffalo Bills during the 2025 NFL season. The Bills won 31-19.

Buffalo Bills quarterback Josh Allen rushes for 15 yards against the New Orleans Saints during Week 4 of the 2025 NFL season.

Buffalo Bills quarterback Josh Allen rushes for 27 yards against the New Orleans Saints during Week 4 of the 2025 NFL season.

Josh Allen with a 28-yard touchdown pass to Dalton Kincaid vs. New Orleans Saints, 09/28/2025

Josh Allen rushes for a 5-yard touchdown vs. New Orleans Saints, 09/28/2025

Buffalo Bills safety Cole Bishop intercepts the pass from New Orleans Saints quarterback Spencer Rattler during Week 4 of the 2025 NFL season.

Buffalo Bills quarterback Josh Allen completes a 17-yard pass to wide receiver Keon Coleman against the New Orleans Saints during Week 4 of the 2025 NFL season.

James Cook sets a new Buffalo Bills franchise record as he rushes for a touchdown in eight consecutive games.

Khalil Shakir with a 43-yard touchdown catch from Josh Allen vs. New Orleans Saints, 09/28/2025

Look back at the Bills 31-21 win over the Dolphins in Week 3 from Chris Brown and Eric Wood in the broadcast booth!

Take a look back at all of the action from the 31-21 win in Week 3 over the Miami Dolphins!

Buffalo Bills' top plays vs. the Miami Dolphins during Week 3 of the 2025 NFL season.

Buffalo Bills quarterback Josh Allen's best plays from his record-breaking game vs. the Miami Dolphins during Week 3 of the 2025 NFL season in which he became the fastest player in NFL history to reach 300 career touchdowns (including postseason). The Bills won 31-21 at Highmark Stadium.

Highlights from the Week 3 matchup between the Miami Dolphins and the Buffalo Bills from Highmark Stadium during the 2025 NFL season.

Buffalo Bills running back James Cook best plays from 118-yard game vs. Dolphins in Week 3 of 2025 NFL Season. The Bills won 31-21 at Highmark Stadium.

Josh Allen connects with Elijah Moore for 30-yard gain

Terrel Bernard intercepts the Tua Tagovailoa pass vs. Miami Dolphins, 09/18/2025

Khalil Shakir catches a 15-yard Touchdown from Josh Allen in the fourth quarter vs. Miami Dolphins, 09/18/2025

Buffalo Bills quarterback rushes for 19 yards shown on "Thursday Night Football Prime Vision" to get into the red zone.

Buffalo Bills tight end Dalton Kincaid catches a 19-yard pass from quarterback Josh Allen against the Miami Dolphins.

Buffalo Bills linebacker Shaq Thompson puts a huge hit on Miami Dolphins running back De'Von Achane after catch.

Josh Allen finds Tyrell Shavers for a 17-yard gain and a Buffalo Bills first down.

Buffalo Bills running back James Cook's 26-yard rush is highlighted on "Thursday Night Football Prime Vision".