James Cook's best runs from 154-yard game vs. Chargers | Week 3

Watch the best plays by Buffalo Bills running back James Cook against the Los Angeles Chargers in Week 3 of the 2026 NFL season.

Highlights from the Week 3, 2026 matchup between the Los Angeles Chargers and the Buffalo Bills.

Bills RB James Cook rushes for a 3-yard Touchdown vs. Los Angeles Chargers to extends the Bills lead in the fourth quarter.

The Buffalo Bills defense forces a turnover on downs.

Buffalo Bills running back James Cook rushes for 23 yards.

Buffalo Bills quarterback Josh Allen rushes for a 1-yard touchdown to give Buffalo the lead in the fourth quarter.

C.J. Gardner-Johnson intercepts the Justin Herbert pass vs. Los Angeles Chargers, 09/27/2026

Buffalo Bills quarterback Josh Allen completes a 37-yard pass to wide receiver Keon Coleman.

Josh Allen rushes for a 1-yard Touchdown in Week 3 vs. Los Angeles Chargers.

Buffalo Bills linebacker Greg Rousseau sacks Chargers quarterback Justin Herbert.

Buffalo Bills kicker Tyler Bass makes a 28-yard field goal.

Buffalo Bills quarterback Josh Allen's pass was tipped by the Chargers and he catches it for a 1-yard gain.

Watch the Bills' Week 2 top plays against the Detroit Lions as Buffalo scores 41 points in the Inaugural Season game at Highmark Stadium

NFL Highlights from the Buffalo Bills 41-31 victory over the Detroit Lions. QB Josh Allen threw for 3 touchdowns and ran for two more as Buffalo wins its first regular season Highmark Stadium.

Buffalo Bills running back James Cook's best plays from his 139-yard game vs. the Detroit Lions during Week 2 of the 2026 NFL season.

Buffalo Bills quarterback Josh Allen's best plays from his five touchdown game vs. the Detroit Lions in Week 2 of the 2026 NFL season.

Buffalo Bills running back James Cook scores his first touchdown of the 2026 NFL season.

Bills RB James Cook's wicked juke move sparks 22-yard run that nearly yields pylon access. Bills-Lions Highlights.

Buffalo Bills quarterback Josh Allen scores his second rushing touchdown of the night.

Buffalo Bills outside linebacker Bradley Chubb sack's Detroit Lions quarterback Jared Goff.

Buffalo Bills quarterback Josh Allen's throws his third touchdown pass of first half to tight end Dalton Kincaid.

Bills RB James Cook rushes for a 35-yard Gain vs. Detroit Lions, 09/17/2026

Buffalo Bills quarterback Josh Allen throws this fourth touchdown pass of the 2026 NFL season to tigt end Dawson Knox.

Buffalo Bills quarterback Josh Allen throws a 22-yard pass to Coleman.

Buffalo Bills linebacker Greg Rousseau sack's Detroit Lions quarterback Jared Goff for the second time in the first quarter.