James Cook's best runs from career-high 216-yard, 2-TD game vs. Panthers | Week 8

Watch highlights of Buffalo Bills running back James Cook's best runs from Week 8 where he scored twice and amassed 216 rushing yards against the Carolina Panthers during the 2025 NFL season.

Highlights from the Week 8 matchup between the Buffalo Bills and the Carolina Panthers during the 2025 NFL season. Buffalo won 40-9 in convincing fashion to improve to 5-2.

James Cook rushes for a 21-yard touchdown vs. Carolina Panthers, 10/26/2025

Josh Allen with a 54-yard touchdown pass to Khalil Shakir vs. Carolina Panthers, 10/26/2025

Josh Allen rushes for a 1-yard touchdown vs. Carolina Panthers, 10/26/2025

A.J. Epenesa intercepts the Andy Dalton pass vs. Carolina Panthers, 10/26/2025

Buffalo Bills running back James Cook scores on a 64-yard touchdown run against the Carolina Panthers during Week 8 of the 2025 NFL season.

Buffalo Bills kicker Matt Prater makes a 43-yard field goal against the Carolina Panthers during Week 8 of the 2025 NFL season.

Andy Dalton fumbles, Christian Benford recovers vs. Buffalo Bills, 10/26/2025

Buffalo Bills kicker Matt Prater makes a 45-yard field goal against the Carolina Panthers during Week 8 of the 2025 NFL season.

Greg Rousseau gets up to block an Atlanta field goal in the fourth quarter of Monday Night Football

Buffalo Bills defensive tackle Ed Oliver sacks Atlanta Falcons quarterback Michael Penix Jr. for a 13-yard loss as the multiple Bills' defenders put pressure on the the Atlanta QB.

Josh Allen with a 16-yard touchdown pass to Ray Davis vs. Atlanta Falcons, 10/13/2025

Buffalo Bills cornerback Taron Johnson deflects Atlanta Falcons quarterback Michael Penix Jr.'s fourth-down pass, giving Buffalo possession.

Khalil Shakir shimmies and shakes for extra yardage and a Bills first down

Javon Soloman brings down Michael Penix Jr. for third down sack

Josh Allen with a 19-yard touchdown pass to Dawson Knox vs. Atlanta Falcons, 10/13/2025

Josh Allen delivers a 45 yard dime to Joshua Palmer on Monday Night Football.

Highlights from the Week 5 matchup between the New England Patriots and the Buffalo Bills during the 2025 season.

Buffalo Bills quarterback Josh Allen finds tight end Dalton Kincaid for 23-yard gain.

Josh Allen with a 2-yard touchdown pass to Keon Coleman vs. New England Patriots, 10/05/2025

Curtis Samuel catches for a 6-yard Touchdown vs. New England Patriots, 10/05/2025

Buffalo Bills tight end Dalton Kincaid secures 20-yard gain off quarterback Josh Allen pass.

Buffalo Bills quarterback Josh Allen scrambles for a 19-yard gain.

Buffalo Bills kicker Matt Prater kicks a 31-yard field goal.