The Bills made the following draft picks in the 2024 NFL Draft:
- Round 2: WR Keon Coleman, Florida State, No. 33 overall (from Panthers)
- Round 2: S Cole Bishop, Utah, No. 60
- Round 3: DT DeWayne Carter, Duke, No. 95 (from Chiefs)
- Round 4: RB Ray Davis, Kentucky, No. 128
- Round 5: C/G Sedrick Van Pran-Granger, Georgia, No. 141 (from Panthers)
- Round 5: LB Edefuan Ulofoshio, Washington, No. 160 (from Packers)
- Round 5: DE Javon Solomon, Troy, No. 168
- Round 6: T Tylan Grable, UCF, No. 204
- Round 6: CB Daequan Hardy, Penn State, No. 219
- Round 7: G Travis Clayton, International Player Pathway, No. 221 (from Chiefs)
