Safeties Micah Hyde and Rafael Bush along with TE Charles Clay didn't practice much at all this week, but there is still hope for Sunday as all three are listed as questionable for the Titans game.
Hyde was seen as a long shot for this week's game when he was labeled week to week by head coach Sean McDermott on Monday after sustaining a groin injury in the first quarter of last week's game at Green Bay.
Meanwhile Bush was a surprise add to the injury report this week with a shoulder injury. He was the primary fill in for Hyde at safety last week.
If neither of them are able to play those duties could fall to rookie Siran Neal.
Neal has played every week on special teams, but his time on defense has been very limited, though he did notch a sack Sunday.
Another option if both Bush and Hyde can't go is practice squad S Dean Marlowe. McDermott confirmed that with just two healthy safeties on the roster in Neal and Jordan Poyer, that calling Marlowe up is a distinct possibility.
Marlowe actually has five NFL regular season games under his belt from his time with the Carolina Panthers between 2015 and 2016. He also has been playing in this defensive system for the last three-plus years.
Charles Clay, who was able to play despite being limited by shoulder and hip injuries last week, came into this week with an ankle injury that kept him out of practice on Thursday and Friday.
Set to help fill the void if Clay can't play are tight ends Jason Croom, Khari Lee and Logan Thomas.
S Rafael Bush - shoulder
TE Charles Clay – ankle
S Micah Hyde – groin
The Titans will definitely be without a pair of defensive starters on Sunday. Starting LB Wesley Woodyard and starting S Kenny Vaccaro are both out with shoulder and elbow injuries respectively. Backup offensive tackle Dennis Kelly is questionable even though he was a full practice participant on Friday.
S Kenny Vaccaro - elbow
LB Wesley Woodyard - shoulder
OT Dennis Kelly - illness