Buffalo Bills head coach Joe Brady ruled out two players and listed three others as questionable for Sunday's matchup against the Chargers.
DB Jordan Hancock (hamstring) and DL T.J. Sanders (illness) will be OUT for Week 3, while WR DJ Moore (shoulder), WR Keon Coleman (ankle) and DL Ed Oliver (hip) are QUESTIONABLE.
Brady said Moore and Coleman will be game time decisions for their availability; both players were limited in Friday's practice.
"I'm going to give them all the way through till game time," Brady shared. "And I have confidence in them. When they're ready to go, they'll be ready to go."
Oliver was a full participant in Friday's practice after being limited Thursday.
Hancock's hamstring injury popped up during practice this week, and Sanders had an appendectomy.
The good news for the Bills is that RB Ty Johnson is expected to make his season debut on Sunday after missing the first two weeks with a hamstring injury.
"Ty Johnson will be good to go," Brady said.
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Swipe to see the best photos from the Buffalo Bills practice at the Kaleida Health Performance Center in Orchard Park, NY.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
Buffalo Bills Week 3 Practice, September 24, 2026 at the Kaleida Health Performance Center.
