Buffalo heads down to Miami in Week 10 for Sunday's game against the Dolphins. The Bills have an opportunity to win their seventh consecutive regular season matchup against the AFC East opponent. Kickoff is slated for 1 p.m. ET.

Miami is third in the AFC East with a 2-7 record, and its two wins have come against the New York Jets and Atlanta Falcons. Buffalo is second in the division with a 6-2 record just behind the New England Patriots. This will be the second meeting between the Bills and Dolphins in 2025, and Buffalo seeks its second win over Miami following a 31-21 victory in Week 3.

Injury updates from first practice of Week 10

On Wednesday, Bills head coach McDermott provided an injury report prior to practice.

Defensive end Joey Bosa (wrist), running back James Cook (ankle), defensive end A.J. Epenesa (concussion), cornerback Taron Johnson (groin), defensive tackle DaQuan Jones (calf) and linebacker Shaq Thompson (hamstring) did not practice.

Cook sustained his injury during the Kansas City game and was sore following the game, according to McDermott. Though Jones isn't on a veteran rest day, McDermott said not practicing on Wednesday was in ways a "rest in terms of his rehab schedule."

Linebacker Terrel Bernard and wide receiver Joshua Palmer were limited on Wednesday.

Cornerback Christian Benford was added to the injury report after practice with a groin injury. He was listed as limited.

Buffalo meets Miami for second time in 2025 after 31-21 Week 3 win

Week 3's game ended with quarterback Tua Tagovailoa throwing a late, fourth quarter interception with Miami down seven points. Quarterback Josh Allen finished with three pass touchdowns and no interceptions. Cook ran for 108 yards and one touchdown on 19 carries.

While the Bills beat the Dolphins at home earlier in the 2025 season, McDermott isn't underemphasizing the game ahead of them. As his offense and defense takes steps forward, playing with a more aggressive attitude as seen against Kansas City, McDermott still knows there's more to his team and how Buffalo is performing now is not the end-all-be-all.

"We're moving in the right direction. We are, and I applaud the staff and the coaches for it, they've done a really good job. Players have recalibrated a little bit and done everything that we've asked them to do," McDermott said. "Now we've got to continue to go because we're not where we need to be. This is a big divisional game down there away, and so we've got to put a good week of preparation in."

Since the last time the teams met, the Dolphins agreed to part ways with general manager Chris Grier. After their Week 9 game, senior personnel executive Champ Kelly took over as interim general manager. Sunday will be their first game with Kelly in this role. Miami also traded linebacker Jaelan Phillips to the Eagles for a third-round pick in the 2026 NFL Draft. Phillips played 73 percent of the team's defensive snaps in 2025 before the trade and logged three sacks.

"We can't control any of that (trades). At the end of the day, we've got to get ourselves ready to go, and our level of play is what matters most, and what impacts that the most is how we prepare during the week and how we handle ourselves," McDermott said. "If we're worried about that, then we're not going to be able to play to the level we need to play to win the game. Very competitive team, and we have a ton of respect for their game, so we've got to get ourselves ready to go."

Bills' offense is becoming the two-dimensional threat they want

Against the Chiefs, Buffalo's pass game elevated after a quiet day against the Panthers off the bye week. McDermott and offensive coordinator Joe Brady emphasized the importance of having a two-dimensional offense as a reason for success.

With Cook controlling the run game and the tight end room as a whole uplifting the pass game with quarterback Josh Allen, the Bills have the No. 1 total offense in the NFL in 2025. This is the first time with Josh Allen under center that the Bills rank at the top of league in total offense with 385.5 yards per game.

The offense continues elevating week-to-week, getting guys involved depending on the game; 10 different receivers recorded a reception against the Chiefs.

Though wide receiver Keon Coleman has the "microscope" on him, as described by general manager Brandon Beane, Coleman's growth is continuing. That includes taking on whatever role the offense needs him to, whether it's in the pass game as a receiver, throwing up blocks or contributing to the run game.

"Everybody's got their own skill set that we need to continue to utilize at a higher level, and that starts with myself. Last game, we completions to 10 different targets last week," Allen said. "And that's what we're going to need to do — we're going to need to utilize everybody, and guys are going have to step up and make some plays, but I have to give them the opportunity to do that."

In the tight end room, McDermott said that Dalton Kincaid's growth is unsurprising in all areas of offense. Kincaid had six targets for over 100 yards and a touchdown in Week 9. McDermott isn't expecting the same player or players to be hot every game, but the effort and identity is taking over the Bills as a whole no matter who has the ball in their hand.

"I love nastiness, I love physicality. That's how we play here in Buffalo," McDermott said. "So, if you want to be good, you've got to bring that to the table in all three phases."

Injuries allow young defensemen to prove themselves

Defensive end Michael Hoecht tore his Achilles against the Chiefs on Sunday and will be out for the remainder of the season.

Due to Hoecht's injury joining others on defense, McDermott said it's an opportunity for younger players on the depth chart to step up. Safety Jordan Hancock, cornerback Maxwell Hairston, defensive tackle Deone Walker, defensive end Landon Jackson and safety Cole Bishop are among those young defenders who have chances to make plays.

Walker said Jones, Jordan Phillips and Ed Oliver are the defensive tackles taking him under their wings. Safety Jordan Poyer is acting as a role model for Bishop and Hancock.

That leadership, especially on defense due to injuries, is something McDermott commended. While Hairston, Bishop, Walker and Hancock are growing week-to-week, Landon Jackson is a player who hasn't had a consistent or newly consistent role on the field.

"With the injury situation and some of the holes … [Jackson] needs to step up, and he knows that. [Jackson's] been very conscientious," McDermott said of the rookie defensive end. "…the hardest part of not playing week to week in the NFL is the team moves, and you've got to make sure that you're moving with it because when you play and the team plays, there's development. You kind of get into a rhythm, and so the players that aren't playing have to find the best way to move with the team as the team moves. So we'll see where that goes this week for [Jackson], but I know he's been working hard behind the scenes."

One thing McDermott and defensive coordinator Bobby Babich emphasized to Jackson over the weeks is being prepared to step up into a role whenever his time comes, whether related to injuries or not.

"Quite a bit throughout these past few weeks of being active, inactive," Jackson said of having conversations with McDermott and Babich. "Just saying that I'm looking good playing, I'm getting better every day and just continue to grow."