| 2025-05-01 | Buffalo Bills 2025 opponents finalized |
| 2025-05-01 | Time & Date Announced for 2025 NFL Schedule Release |
| 2025-05-01 | 'Mental Moments' | Why the Bills are prioritizing Mental Health and Wellness Awareness Month |
| 2025-05-02 | How Bills fans can sign up to be cast as an extra for Hallmark's Holiday Touchdown: A Bills Love Story |
| 2025-05-02 | Buffalo Bills, Wegmans team up to support local food-insecure families with food allergies and special diet needs | 2025 |
| 2025-05-02 | Bills RB Ray Davis honored with 2025 Advocacy Award for Mental Health Awareness |
| 2025-05-03 | One thing to know about every pick from the Buffalo Bills 2025 Draft Class |
| 2025-05-05 | Bills add free agent WR Elijah Moore on one-year deal |
| 2025-05-07 | 'Mental Moments' | Three strategies on how to practice gratitude |
| 2025-05-09 | Buffalo Bills ink six players from 2025 Draft Class to rookie contracts |
| 2025-05-09 | Meet the Buffalo Bills 2025 Undrafted Free Agents |
| 2025-05-09 | Bills claim DT Casey Rogers off waivers from New York Giants |
| 2025-05-09 | Notebook | Maxwell Hairston reunites with UK teammate, defensive line additions asses first day of Bills rookie minicamp |
| 2025-05-12 | Buffalo Bills Announce Verizon as Official 5G Network and Founding Partner of New Highmark Stadium |
| 2025-05-12 | How ‘human encyclopedia’ Adam Henry’s pursuit of doctorate degree translates to his role as Bills WR coach |
| 2025-05-13 | The Last Call | Buffalo Bills to celebrate Farewell Season at Highmark Stadium with logo, jersey patch and more |
| 2025-05-14 | Top 9 things to know about the Bills 2025 schedule |
| 2025-05-15 | 'Mental Moments' | How to practice daily affirmations and why your inner voice matters |
| 2025-05-15 | Bills 2025 schedule release | All 17 games officially announced |
| 2025-05-16 | Buffalo Bills announce return to St. John Fisher University for 2025 Training Camp |
| 2025-05-19 | Sean McDermott, Dion Dawkins, Damar Hamlin & more to appear in Hallmark's Holiday Touchdown: A Bills Love Story
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| 2025-05-20 | Bills sign WR Kristian Wilkerson to one-year contract, release WR Hal Presley III |
| 2025-05-20 | Bills announce 2025 preseason schedule |
| 2025-05-21 | ‘There’s a lot of empowerment’ | Bills host first-ever Modified Girls Flag Football Skills Challenge |
| 2025-05-22 | 'Mental Moments' | Why breathing is a powerful tool for our mental health |
| 2025-05-27 | OTA Notebook | Bills HC Sean McDermott on James Cook's absence, Joey Bosa's injury, 'Hard Knocks' selection and Vince Carter appearance |
| 2025-05-28 | M&T Bank and Buffalo Bills Extend ‘Official Bank’ Partnership |
| 2025-05-29 | Erie County announced as HEARTSafe community for widespread CPR training and AED access |
| 2025-05-29 | 'Mental Moments' | How to ask for help and lean on others for support |
| 2025-05-30 | Buffalo Bills announce promotions and additions to personnel and analytics staffs for 2025 season |