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Bills DE A.J. Epenesa joined One Bills Live after practice and talked about the defensive line adjustments for this weekend's game in Detroit. He discussed the AFC standings and the teams contending with them at the top. He then talked about the team's mentality entering their Week 15 matchup against the Lions and the players who have stepped up this season. Finally, he answered a fan question in this week's Timbits® Timeout presented by Tim Hortons.

ESPN NFL analyst Dan Orlovsky joined One Bills Live and recapped the Bills back-and-forth affair in Los Angeles against the Rams and Josh Allen's spectacular performance in the loss. He shared his thoughts on the Bills final offensive drive and how the end of the game played out. He transitioned to the defensive side of the ball to discuss the struggles in slowing down Matthew Stafford and what they can do this weekend against the Lions. He then talked about the importance of the Week 15 matchup, Buffalo's offensive challenges against a tough Detroit defense, and the matchup against the Lions offense. Finally, he recapped his role in ESPN's alternative 'Simpsons' broadcast on Monday Night Football.

Chris Brown, Steve Tasker, and Maddy Glab shared their thoughts on the Bills 44-42 loss to the Rams on Sunday. The trio took listener questions following the Week 14 game and then shifted gears to next weekend's matchup with the Lions in Detroit.

NFL Films senior producer Greg Cosell joined One Bills Live to break down this weekend's matchup in Los Angeles against the Rams. He shared his thoughts on the Rams offense, including the pass game concepts led by Matthew Stafford. He then discussed Los Angeles' run game struggles on defense, their pass rush ability, and the battle in the NFC West. Finally, he talked about Matt Milano's return to the lineup and the importance of having him in the lineup on Sunday.

Bills Hall of Fame RB Thurman Thomas joined One Bills Live and discussed his impressions of Josh Allen and the Bills win last weekend in the snow over the 49ers. He shared his thoughts on the team heading out west to face the Rams in Week 14 and the success they can have in the run game. He then chimed in on the topic of the day of what's more impressive - the Bills offense scoring 30+ points in the last six games or the defense's ability to have a takeaway in every game this season?

Bills offensive lineman Alec Anderson joined One Bills Live and talked about his bye week engagement, his first snow game last weekend against the 49ers, and his bare-belly celebration in the win. He discussed the versatility he brings to the offensive line, the run game success, and heading back home to the west coast to face the Rams this weekend. He also shared his thoughts on teammate Mack Hollins and his demeanor switch he has on game days. Alec then answered a fan question in this week's Timbits® Timeout presented by Tim Hortons.

ESPN NFL analyst Dan Orlovsky joined One Bills Live for his weekly appearance. He discussed the MVP race following Josh Allen's performance in the team's win over the 49ers and the team's goals as the season nears the stretch run. He looked at this weekend's matchup with the Rams and how the run game could be key to Buffalo's offensive success. On defense he examined controlling the Rams run game and offense led by Matthew Stafford. Finally, he talked about the lateral TD between Josh Allen and Amari Cooper and the contenders and pretenders as the playoffs near.

Bills team reporter Maddy Glab joined One Bills Live to hand out her weekly Maddy Awards following the team's AFC East clinching win over the 49ers. She shared praise for Josh Allen's lateral TD, the rushing attack led by James Cook, the offensive line's production in the snow, and Greg Rousseau's dominance on the D-line. She then gave awards to Alec Anderson and head coach Sean McDermott's celebrations in the snow and the return of veteran LB Matt Milano to the lineup.

Bills radio color analyst and former Pro Bowl center Eric Wood joined One Bills Live and shared his biggest takeaways from Buffalo's 35-10 win over the 49ers, including the offensive output led by Josh Allen and the defensive efforts to get multiple turnovers. He discussed the Bills variety on offense teams have to prepare for, Matt Milano's return to the lineup, and the AFC landscape after Week 13.

Former Bills QB Doug Flutie joined One Bills Live and talked about his excitement in returning to Orchard Park as this week's BFLO Store Legend of the Game when the Bills host the 49ers Sunday night. He shared some memories playing against San Francisco, what he's looking forward to doing in the Western New York area, and his efforts with the Doug Flutie, Jr. Foundation for Autism.

NFL Films senior producer Greg Cosell joined One Bills Live for his weekly appearance. He talked about the QB situation with the 49ers and the limitations they may have if Brandon Allen has to start over Brock Purdy. He discussed Kyle Shanahan's offensive scheme, their offensive line struggles, and how the Bills defense will match up. On the other side of the ball, he shared his thoughts on how the Bills may have success on the ground in the run game, San Francisco's red zone issues, and the impact of the Bills potentially winning their division so early in the season.

Bills offensive guard O'Cyrus Torrence joined One Bills Live after today's practice. He discussed his bye week, resetting for the final stretch of the season, and his performance controlling Chiefs DT Chris Jones in their Week 11 win. He then talked about his transition from his rookie season to now and this weekend's game vs. the 49ers. Finally, he answered a fan question in this week's Tim Hortons Timbits® Timeout.

ESPN NFL analyst Dan Orlovsky joined One Bills Live for his weekly appearance and discussed where the Bills stand after their 9-2 start and the team's health coming out of the bye. He shared his thoughts about the strategy to bringing Matt Milano back into the lineup and the team's approach to the stretch run of the season. Dan looked ahead to this weekend's game with the 49ers, including San Francisco's issues along the offensive line, the difference makers for its offense, and Kyle Shanahan's offensive approach this season. Finally, he talked about the matchup for the Bills offense, the advantages they have against the 49ers defense, and a quick look at the landscape of the AFC.

NFL Films senior producer Greg Cosell joined One Bills Live for his weekly appearance. He talked about Josh Allen's play in the win over the Chiefs, the offense executing against a tough Chiefs defense, and the offensive line's performance. He shared his thoughts on the defense's takeaway prowess, their ability to create pressure, and took a quick look at the Week 13 game against the 49ers.

ESPN NFL analyst Dan Orlovsky joined One Bills Live for his weekly appearance and shared his biggest takeaways from the Bills 30-21 win over the Chiefs. He broke down Josh Allen's heroic TD late in the 4th quarter, the concept of the play offensively and defensively, and why Josh's decision making was so impressive. He went on to discuss the biggest plays from the game, the Bills tendency to run on first down, and the defensive pressure Buffalo put on Patrick Mahomes. Finally, he talked about the player development the Bills have defensively, how it's led to so much success this season, and the landscape of the AFC down the stretch.

Bills team reporter Maddy Glab handed out her Maddy Awards following the team's 30-21 win over the Chiefs. She gave accolades to Josh Allen, Curtis Samuel, Terrel Bernard, James Cook, Ryan Van Demark, and O'Cyrus Torrence. She also gave kudos to Buffalo's fast start on defense controlling Patrick Mahomes.

Bills radio color analyst and former Pro Bowl center Eric Wood joined One Bills Live and shared his biggest takeaways from the Bills 30-21 win over the Chiefs. He discussed the landscape of the AFC following Week 11 and which teams have a realistic shot at challenging for the top of the conference. He went on to talk about the offensive line's performance in the win over Kansas City, the current injury situation for Buffalo, and the impressive schemes the defense offered. Finally, he shared his current thoughts on Josh Allen's bid for MVP.

NFL Films senior producer Greg Cosell joined One Bills Live for his weekly appearance. He shared his thoughts on this weekend's game between the Bills and the Chiefs. He discussed the Chiefs defensive backfield, including Trent McDuffie up against the Bills receiving corps, the use of 12-personnel, and where the Bills might find a weakness in the Chiefs defense. He then looked at Kansas City's offense and how the Bills might game plan to slow down Patrick Mahomes and company.

Comedian and actor Sebastian Maniscalco joined One Bills Live ahead of his Rochester and Buffalo tour stops this weekend. He talked about his rise in comedy and the ups and downs that came along with it. He talked about his upcoming standup special on Hulu, his second season of 'Bookie' on Max, and his love for the NFL and the Chicago Bears. Finally, he answered some rapid fire questions about being Italian.

NFL on CBS studio analyst and former NFL MVP Matt Ryan joined One Bills Live. He shared his thoughts on bringing The NFL Today pregame show to Highmark Stadium and the anticipation for the Week 11 matchup between the Bills and Chiefs. He discussed why this is the game of the year, the Chiefs ability to remain undefeated, and if the Bills can continue to deliver takeaways on defense.

Bills radio color analyst/former Pro Bowl center Eric Wood joined One Bills Live and discussed the variety of offensive packages the Bills offense can offer the Chiefs, if this game will be a precursor to a playoff matchup, and the player availability for an injured Bills team. He went on to talk about the efficiency on third down, the ability for Buffalo to spread the ball around, and the Chiefs stance to remain undefeated.

Bills DE Greg Rousseau joined One Bills Live after today's practice. He talked about his performance against the Colts in Week 10, the defense's ability to rack up turnovers, and the changes this season due to injuries. He then discussed the second half adjustments the defense makes to lock down opponents and looked ahead to this weekend's game against the Chiefs. Finally, he answered a fan question in this week's Timbits® Timeout presented by Tim Hortons.

ESPN NFL analyst Dan Orlovsky joined One Bills Live for his weekly appearance on the show. He recapped the Bills 30-20 win over the Colts, the defensive effort in the victory, and Buffalo's success in the red zone. He then transitioned to this week's game with the Chiefs. He discussed why Kansas City is such a tough matchup, where the Bills might have to focus their approach, and the importance of coaching schemes.

Bills team reporter Maddy Glab handed out her Week 10 Maddy Awards on One Bills Live following the Bills 30-20 win over the Colts. She honored Taron Johnson, Josh Allen, Mack Hollins, and Damar Hamlin. She also gave accolades to the Bills defense with their 4 turnovers and second half run stopping efforts.

NFL Films senior producer Greg Cosell joined One Bills Live and previewed this weekend's matchup between the Bills and the Colts. He discussed how the Bills offense could look different with the absence of WR Keon Coleman, and the questionable status of WR Amari Cooper- whose availability will be evaluated on Sunday ahead of the game. He also gave his thoughts on what the Bills defensive plan could look like against Jonathan Taylor.