| 2022-01-01 | NFL game predictions | Bills vs. Falcons | Week 17 |
| 2022-01-01 | Bills elevate DT Eli Ankou |
| 2022-01-02 | What Bills fans need to know about the 2021 AFC playoff race | Week 17 |
| 2022-01-02 | Emmanuel Sanders inactive for Bills vs. Falcons | Week 17 |
| 2022-01-02 | Bills vs. Falcons | How to watch, stream, and listen | Week 17 |
| 2022-01-02 | Bills 29, Falcons 15 | Game recap, highlights & photos |
| 2022-01-02 | Bills clinch third consecutive playoff berth with win over Falcons |
| 2022-01-02 | Top 3 things we learned from Bills vs. Falcons | Week 17 |
| 2022-01-03 | Sean McDermott earns praise from Marv Levy after a fourth playoff berth |
| 2022-01-03 | Regular Season Finale vs Jets moved to 4:25 PM at Highmark Stadium |
| 2022-01-03 | Bills players eye a bigger prize after clinching a playoff spot at home |
| 2022-01-03 | National analysts share these opinions on the Bills after securing a 2021 playoff berth |
| 2022-01-04 | How the Bills can clinch the AFC East title | Week 18 |
| 2022-01-04 | Do these Bills have a chance to win the NFL's top 2021 awards? |
| 2022-01-05 | Top 6 storylines to follow for Bills vs. Jets | Week 18 |
| 2022-01-06 | How the Bills continue to stay humble and hungry amid this run of sustained success |
| 2022-01-06 | Steve Tasker set to appear as the Bills Legend of the Game | Week 18 |
| 2022-01-06 | Buffalo Bills name FanDuel Group as Official Mobile Sports Betting Partner |
| 2022-01-06 | Snow shovelers needed at Highmark Stadium | Week 18 |
| 2022-01-07 | 5 things to watch for in Bills vs. Jets | Week 18 |
| 2022-01-07 | Emmanuel Sanders listed as doubtful, Efe Obada out for Bills vs. Jets | Week 18 |
| 2022-01-08 | NFL game predictions | Bills vs. Jets | Week 18 |
| 2022-01-08 | 'Not all about the game' | Bills players award five $50K grants to support non-profits |
| 2022-01-08 | What Bills fans need to know about the 2021 AFC playoff race | Week 18 |
| 2022-01-09 | Marquez Stevenson designated inactive for Bills vs. Jets | Week 18 |
| 2022-01-09 | Bills vs. Jets | How to watch, stream, and listen | Week 18 |
| 2022-01-10 | Bills 27, Jets 10 | Game recap, highlights & photos |
| 2022-01-10 | Bills claim back-to-back AFC East titles |
| 2022-01-10 | Top 3 things we learned from Bills vs. Jets | Week 18 |
| 2022-01-10 | Bills' opponents for 2022 finalized |
| 2022-01-10 | Bills to host 2021 Wild Card playoff game on Saturday at 8:15 pm ET |
| 2022-01-10 | Bills to host Patriots on Super Wild Card weekend |
| 2022-01-10 | Bills to host a 'Win a night in paradise' sweepstakes for Wild Card weekend |
| 2022-01-10 | Why the AFC East-clinching win at home was special for Bills players and coaches |
| 2022-01-11 | Bills defense ends the 2021 regular season as the NFL’s best |
| 2022-01-11 | Bills coaches prep for Wild Card chess match with Patriots |
| 2022-01-11 | How Bills Mafia can help Harrison Phillips win this charity challenge |
| 2022-01-11 | Top 6 storylines to follow for Bills vs. Patriots | Wild Card Weekend |
| 2022-01-11 | What they're saying | National analysts handicap Bills vs. Pats in the Wild Card Round |
| 2022-01-12 | Relying on this has helped the Bills offense develop heading into the playoffs |
| 2022-01-12 | Jim Kelly and Thurman Thomas to appear as the Bills Legends of the game | Wild Card weekend |
| 2022-01-13 | 6 things to watch for in Bills vs. Patriots | Super Wild Card weekend |
| 2022-01-13 | Bills do not use any game status designations for Wild Card game |
| 2022-01-14 | Free Zippo Electric Hand Warmers courtesy of FanDuel Sportsbook to be distributed at Bills vs. Pats game |
| 2022-01-14 | Bills' Jordan Poyer named first team All-Pro |
| 2022-01-15 | Bills welcome Caesars Sportsbook as an official mobile sports betting partner |
| 2022-01-15 | NFL game predictions | Bills vs. Pats | Wild Card Weekend |
| 2022-01-15 | 'The mafia's going to be crazy' | Bills players, fans ready embrace the cold for Saturday's playoff clash against the Pats |
| 2022-01-15 | Bills list seven players inactive for Wild Card game against the Pats |
| 2022-01-16 | Bills vs. Patriots | How to watch, stream, and listen to Saturday's Wild Card playoff game |
| 2022-01-16 | Bills 47, Patriots 17 | Game recap, highlights & photos |
| 2022-01-16 | Bills advance to the Divisional Round of the 2021 NFL playoffs |
| 2022-01-16 | Top 3 things we learned from Bills vs. Patriots | Super Wild Card Weekend |
| 2022-01-16 | Playoff mentality fuels the Bills' five-game win streak and trip to the AFC Divisional Round |
| 2022-01-16 | Dawson Knox and Devin Singletary emerge as bona fide difference makers at the perfect time |
| 2022-01-17 | Buffalo Bills to face the Kansas City Chiefs in 2021 AFC Divisional Round |
| 2022-01-17 | Bills pay tribute to Dr. Martin Luther King |
| 2022-01-18 | Adversity plays a role in the Bills’ growth as they prepare to face a familiar foe |
| 2022-01-18 | What they're saying | Why Bills at Chiefs is the most anticipated game of the divisional round |
| 2022-01-19 | Bills fans help Harrison Phillips earn $5K for his Playmakers Foundation |
| 2022-01-19 | Top 6 storylines to follow for Bills at Chiefs | Divisional Round |
| 2022-01-20 | Bills prepare for a familiar opponent with increased stakes in AFC divisional playoff round |
| 2022-01-20 | Canalside to host Bills Fan Appreciation Skate night on Friday |
| 2022-01-21 | Staying perfect? Buffalo's offense enters Kansas City with these expectations |
| 2022-01-21 | 6 things to watch for in Bills at Chiefs | Divisional Round |
| 2022-01-21 | Bills do not use any game status designations for Divisional Round game |
| 2022-01-21 | Brandon Beane shares his thoughts on Joe Schoen's move to the Giants and what's next for the personnel department |
| 2022-01-23 | NFL game predictions | Bills vs. Chiefs | Divisional Round |
| 2022-01-23 | Still fighting for respect | Bills’ No. 1 defense can take another step against the Kansas City Chiefs |
| 2022-01-23 | Bills deactivate seven players for Divisional matchup at Kansas City |
| 2022-01-23 | Bills at Chiefs | How to watch, stream, and listen to Saturday's Divisional Round game |
| 2022-01-24 | Chiefs 42, Bills 36 in OT | Game recap, highlights & photos | Divisional Round |
| 2022-01-24 | Analysts offer these reactions to Bills at Chiefs overtime thriller in the divisional round | Social Media recap |
| 2022-01-24 | 10 takeaways from the Bills at Chiefs postgame press conferences |
| 2022-01-24 | Top 3 things we learned from Bills at Chiefs | Divisional Round |
| 2022-01-24 | Josh Allen's playoff performance delivers hope for Buffalo |
| 2022-01-25 | 10 things we learned from the Bills' final day of the 2021 season |
| 2022-01-25 | Top 5 things we learned from Sean McDermott's 2021 season wrap-up press conference |
| 2022-01-26 | Bills-Chiefs delivers huge ratings for CBS |
| 2022-01-26 | Bills to pick 25th overall in the 2022 NFL Draft |
| 2022-01-26 | Brotherhood-type bond among Bills creates hope for future after a painful loss |
| 2022-01-26 | Chiefs fans raise $178K and counting for Buffalo's Oishei Children's Hospital |
| 2022-01-27 | GM Brandon Beane shares how he plans to turn pain into progress for the Bills |
| 2022-01-27 | Josh Allen announced he will not play in the 2022 Pro Bowl as an alternate |
| 2022-01-28 | Paige Clark named Bills Season Ticket Member of the Month for January |
| 2022-01-28 | Bills and Sabres announce the 'Better Together' initiative |
| 2022-01-29 | What They’re Saying | NFL analysts assess the Bills’ future in 2022 & beyond |
| 2022-01-31 | How Josh Allen reached the pinnacle of NFL quarterbacking in 2021 |
| 2022-01-31 | Bills Foundation donates $50,000 to the African Heritage Food Co-op |
| 2022-01-31 | Edreys Wajed creates logo for 'Better Together' initiative |
