| 2021-05-01 | 5 things to know about defensive end Boogie Basham |
| 2021-05-01 | 5 things to know about tackle Spencer Brown |
| 2021-05-01 | Top 5 things we learned from the Bills | 2021 NFL Draft night two |
| 2021-05-01 | What Bills fans need to watch for on the final day of the 2021 NFL Draft |
| 2021-05-01 | 3 things to know about tackle Tommy Doyle |
| 2021-05-01 | Bills acquire 203rd and 212th picks from Houston |
| 2021-05-01 | 3 things to know about wide receiver Marquez Stevenson |
| 2021-05-01 | 3 things to know about safety Damar Hamlin |
| 2021-05-01 | 3 things to know about cornerback Rachad Wildgoose |
| 2021-05-01 | 3 things to know about guard Jack Anderson |
| 2021-05-02 | 10 final observations on the Bills' 2021 NFL Draft class |
| 2021-05-02 | NFL analysts provide these grades for the 2021 Bills draft class |
| 2021-05-03 | Bills Today | The Athletic thinks this Bills draft pick will make the biggest impact |
| 2021-05-03 | Bills exercise fifth-year options on Josh Allen and Tremaine Edmunds |
| 2021-05-04 | Bills Today | Buffalo moves up in the latest NFL Power Rankings |
| 2021-05-04 | How Bills fans can win a football autographed by first-round pick Greg Rousseau |
| 2021-05-05 | Bills Today | Bills earn recognition for their draft strategy |
| 2021-05-05 | ‘Shut my mouth and earn respect’ | Bills rookies shift focus to making the 53-man roster |
| 2021-05-06 | Bills Today | Will the Bills play the Buccaneers in the 2021 NFL season opener? |
| 2021-05-06 | Bills set on-sale date for 2021 single game tickets |
| 2021-05-07 | Bills Today | Josh Allen wants to achieve this goal for the city of Buffalo |
| 2021-05-10 | Bills Today | Michael Robinson is most excited to see this Bills playoff rematch in 2021 |
| 2021-05-12 | Bills Today | How to watch the 2021 Bills schedule release coverage |
| 2021-05-12 | Bills to host the Steelers on 2021 NFL Kickoff Weekend |
| 2021-05-12 | 10 things Bills fans need to know about the 2021 NFL schedule |
| 2021-05-13 | Bills Today | NFL Network makes this 'wins total' prediction for Buffalo in 2021 |
| 2021-05-13 | Get to know these 6 Bills undrafted free agents |
| 2021-05-13 | Bills sign free agents Mike Bell and Steven Gonzalez |
| 2021-05-14 | Bills Today | Bills photographer earns recognition from the Pro Football Hall of Fame |
| 2021-05-14 | Bills announce additional 2021 rookie minicamp participants |
| 2021-05-15 | Bills rookies develop chemistry in first on-field action |
| 2021-05-16 | Bills sign LB Joe Giles-Harris |
| 2021-05-17 | Bills Today | Zack Moss’s new podcast “Moss Mode Show & Friends” is coming soon |
| 2021-05-17 | Bills and Sabres to celebrate 716 Day with 'Give 716' |
| 2021-05-18 | Bills Today | Bleacher Report gives the Bills this offseason grade |
| 2021-05-18 | Bills welcome Wesley Clark and Peshkin Law |
| 2021-05-18 | 5 things to know about these moves in the Bills player personnel department |
| 2021-05-19 | Bills Today | Is Josh Allen about to enjoy an MVP season? |
| 2021-05-19 | What they're saying | NFL analysts make these record predictions for the Bills' 2021 season |
| 2021-05-20 | Bills Today | Is this defensive lineman set to breakout in 2021? |
| 2021-05-20 | DT Treyvon Hester signs one-year deal with Bills |
| 2021-05-20 | How to watch a new episode of 'Buffalo Bills: Embedded' on Thursday, May 20 |
| 2021-05-21 | Bills Today | Christian Wade is excited for Efe Obada to join the Bills family |
| 2021-05-21 | Bills sign rookie safety Damar Hamlin |
| 2021-05-24 | Bills Today | CBS Sports insider is confident the Bills will win the division in 2021 |
| 2021-05-24 | Bills, Dion Dawkins help make a fantastic 10th birthday for Ohio boy |
| 2021-05-25 | Bills Today | NFL.com analysts think Sean McDermott can achieve this feat in 2021 |
| 2021-05-25 | 3 things we learned from Sean McDermott | OTAs Week 1 |
| 2021-05-25 | Bills announce season tickets are sold out for 2021 season |
| 2021-05-26 | Bills Today | Can Stefon Diggs take Buffalo to the mountaintop? |
| 2021-05-26 | What we learned from Josh Allen and Tremaine Edmunds | OTAs Week 1 |
| 2021-05-26 | Bills sign wide receiver Lance Lenoir |
| 2021-05-27 | Bills Today | Tremaine Edmunds happy Bills picked up his fifth-year option |
| 2021-05-28 | Bills Today | NFL analyst assesses Buffalo’s chances of winning the AFC East in 2021 |
| 2021-05-28 | Bills sign Reid Ferguson to a three-year extension |
