| 2021-11-01 | Phil Mickelson’s advice helped Josh Allen find his ‘Zen’ in Bills’ win over Miami |
| 2021-11-01 | Top 3 things we learned from Bills vs. Dolphins | Week 8 |
| 2021-11-01 | 13 numbers to know about the Bills after their victory in Week 8 |
| 2021-11-01 | Josh Allen set to appear on Monday Night Football’s Manningcast tonight |
| 2021-11-01 | Sean McDermott announced Jon Feliciano to miss time with a calf injury |
| 2021-11-02 | How Ed Oliver earned a game ball with his disruptive performance against the Dolphins |
| 2021-11-02 | Lackawanna's Adam Tardif and Red Jacket's John Henninger earn high school coach of the week honors | Week 9 |
| 2021-11-02 | Bills remain among the top teams in Week 9 power rankings |
| 2021-11-02 | Bills add WR Austin Proehl and OL Jacob Capra to the practice squad |
| 2021-11-03 | Top 6 storylines for Bills at Jaguars | Week 9 |
| 2021-11-03 | Jordan Poyer named to Pro Football Focus midseason All-Pro team |
| 2021-11-04 | 'Whatever it takes to win' | Bills work to define their identity |
| 2021-11-04 | NFL names Tyler Bass AFC special teams player of the month |
| 2021-11-04 | Why The Athletic named GM Brandon Beane its top NFL executive at the 2021 midseason mark |
| 2021-11-04 | Greg Rousseau named to Pro Football Focus All-Rookie midseason team |
| 2021-11-05 | How respect from the locker room helped Tyler Bass become a premiere NFL kicker |
| 2021-11-05 | 8 things to watch for in Bills at Jaguars | Week 9 |
| 2021-11-05 | Jon Feliciano and Dawson Knox declared out for Bills at Jaguars | Week 9 |
| 2021-11-06 | How McLaren Racing changed two Bills' fans lives forever |
| 2021-11-06 | NFL analysts | Bills at Jaguars game predictions | Week 9 |
| 2021-11-06 | Bills announced these roster moves before the Jaguars game in Week 9 |
| 2021-11-07 | Cole Beasley and Jordan Poyer are active; Justin Zimmer inactive | Bills vs. Jaguars | Week 9 |
| 2021-11-07 | Bills at Jaguars | How to watch, stream, and listen | Week 9 |
| 2021-11-07 | Jaguars 9, Bills 6 | Game recap, highlights & photos |
| 2021-11-08 | Top 3 things we learned from Bills at Jaguars | Week 9 |
| 2021-11-08 | Bills search for answers after tough loss in Jacksonville |
| 2021-11-08 | Bills signed Nick McCloud to the practice squad |
| 2021-11-08 | Sean McDermott earns NFL Salute to Service nomination for the Buffalo Bills |
| 2021-11-08 | Sean McDermott provided these injury updates on Spencer Brown and Dawson Knox |
| 2021-11-09 | Bills seek to get offense on track after historic record streaks come to an end |
| 2021-11-09 | Where do the Bills rank in 2021 NFL power rankings at the midseason point? |
| 2021-11-10 | Top 5 storylines to follow for Bills at Jets | Week 10 |
| 2021-11-10 | Tremaine Edmunds, Zack Moss to miss Wednesday's Bills practice | Week 10 |
| 2021-11-11 | ‘Find ways to stack wins’ | Bills focused on the New York Jets and ending the week 1-0 |
| 2021-11-11 | Bills sign Cam Lewis to 53-man roster; Justin Zimmer place on injured reserve + other moves announced |
| 2021-11-11 | What they're saying | National experts remain optimistic on the Bills at the 2021 midseason mark |
| 2021-11-12 | 7 things to watch for in Bills at Jets | Week 10 |
| 2021-11-12 | Tremaine Edmunds ruled out for Bills at Jets | Week 10 |
| 2021-11-13 | Bills announce Zack Moss has cleared concussion protocol |
| 2021-11-13 | NFL analysts | Bills at Jets game predictions | Week 10 |
| 2021-11-14 | Bills place DT Star Lotulelei on Reserve/COVID-19 list |
| 2021-11-14 | Zack Moss, Matt Breida are active; Jamil Douglas inactive for Bills at Jets | Week 10 |
| 2021-11-14 | Bills at Jets | How to watch, stream, and listen | Week 10 |
| 2021-11-14 | Bills 45, Jets 17 | Game recap, highlights & photos |
| 2021-11-14 | Bills shine in dominant win over the Jets | Social Media Round-Up |
| 2021-11-15 | Top 3 things we learned from Bills at Jets | Week 10 |
| 2021-11-15 | Complementary football helps Bills return to their winning ways |
| 2021-11-15 | Bills established a franchise record for points scored + other numbers we learned in Week 10 |
| 2021-11-15 | Bills activate quarterback Mitchell Trubisky from Reserve/COVID-19 list |
| 2021-11-15 | Josh Allen, Stefon Diggs, Bills defensive backs and Gabriel Davis earn national recognition in Week 10 |
| 2021-11-16 | Jeff Welch of Canandaigua and Eric Valley of Medina earn high school coach of the week honors | Week 11 |
| 2021-11-16 | Marshawn Lynch set to return to Buffalo as the Bills Legend of the game | Week 11 |
| 2021-11-16 | Bills are back in the top 5 in Week 11 NFL power rankings |
| 2021-11-16 | Bills sign Eli Ankou to the practice squad |
| 2021-11-17 | High standard helps Bills boast the NFL’s best defense through 9 games |
| 2021-11-17 | Top 7 storylines to follow for Bills vs. Colts | Week 11 |
| 2021-11-18 | Bills activate Jake Kumerow from reserve/COVID-19 list; Spencer Brown placed on reserve/COVID-19 list |
| 2021-11-18 | Bills and Sabres announce partnerships with Austin Air |
| 2021-11-18 | Will following this trend lead Buffalo's offense to success against the Colts? |
| 2021-11-19 | 7 things to watch for in Bills vs. Colts | Week 11 |
| 2021-11-19 | Bills sign Bobby Hart to the 53-man roster |
| 2021-11-19 | Marshawn Lynch x Bills x 26 Shirts team up on apparel collaboration |
| 2021-11-19 | Tremaine Edmunds listed as questionable for Bills vs. Colts | Week 11 |
| 2021-11-19 | 7 Thanksgiving recipes from your favorite Bills players + Wegmans |
| 2021-11-20 | NFL analysts | Bills vs. Colts game predictions | Week 11 |
| 2021-11-21 | Tremaine Edmunds designated inactive for Bills vs. Colts | Week 11 |
| 2021-11-21 | Bills vs. Colts | How to watch, stream, and listen | Week 11 |
| 2021-11-21 | Colts 41, Bills 15 | Game recap, highlights & photos |
| 2021-11-22 | Bills quickly shift focus to Thursday’s game after tough loss to Indianapolis |
| 2021-11-22 | Top 3 things we learned from Bills vs. Colts | Week 11 |
| 2021-11-22 | How Stefon Diggs & his Bills teammates are making an impact in the community this Thanksgiving |
| 2021-11-23 | Top 5 storylines to follow for Bills at Saints | Week 12 |
| 2021-11-23 | Bills announce Marquez Stevenson designated to return to practice |
| 2021-11-23 | NFL sets date and time for Bills vs. Panthers | Week 15 |
| 2021-11-24 | 6 things we learned from the players ahead of Bills vs. Saints on Thanksgiving |
| 2021-11-24 | Josh Allen leads AFC quarterbacks in Pro Bowl votes |
| 2021-11-24 | No game status designations listed on Bills' final injury report in Week 12 |
| 2021-11-24 | Bills at Saints | 6 things to watch for on Thanksgiving night |
| 2021-11-24 | Steve Tasker named a Pro Football Hall of Fame semifinalist for the Class of 2022 |
| 2021-11-24 | History of Bills Thanksgiving Day games |
| 2021-11-24 | NFL analysts | Bills at Saints game predictions | Thanksgiving |
| 2021-11-25 | ‘Biggest game of the year’ | How the Bills can reclaim national respect on Thanksgiving night |
| 2021-11-25 | Bills activate wide receiver Marquez Stevenson; Ankou and Bryant elevated for Bills-Saints game |
| 2021-11-25 | Isaiah McKenzie, Zack Moss headline Bills inactives | Week 12 |
| 2021-11-26 | 'Patricia Allen Pediatric Recovery Wing' unveiled with Josh Allen at Oishei Children's Hospital |
| 2021-11-26 | Bills at Saints | How to watch, stream, and listen | Week 12 |
| 2021-11-26 | Bills 31, Saints 6 | Game recap, highlights & photos |
| 2021-11-26 | Bills enjoy a fun Thanksgiving night in New Orleans | Social Media Recap |
| 2021-11-26 | Bills fans gain recognition in Pepsi campaign |
| 2021-11-26 | Josh Allen continues to reach rare milestones in his pursuit of perfection |
| 2021-11-26 | Top 3 things we learned from Bills at Saints | Thanksgiving night |
| 2021-11-26 | Bills lose Tre'Davious White for the remainder of the 2021 season |
| 2021-11-27 | What Bills fans need to know about the 2021 AFC playoff race | Week 12 |
| 2021-11-29 | Where the Bills stand in the 2021 AFC playoff race | Week 13 |
| 2021-11-29 | Bills sign cornerback Tim Harris to the practice squad |
| 2021-11-30 | Bills gain some ground in Week 13 NFL power rankings |
| 2021-11-30 | Mark Anderson named Bills Season Ticket Member of the Month for November |
| 2021-11-30 | Bills to launch NFT program during Monday Night Football |
| 2021-11-30 | Bills place CB Tre'Davious White on injured reserve; Tommy Doyle goes on reserve/COVID-19 list |
| 2021-11-30 | Sean McDermott announced these updates on Jon Feliciano, Spencer Brown and Star Lotulelei |
