This is the year of the double-digit favorite in the NFL. More times than not, the double-digit favorite has covered. Somehow, the Jaguars haven't been involved in any of these games. That speaks to their easy schedule, which also speaks to their reasonable claim to being the league's worst team. That's a long way of saying the Bills have the most trustworthy defense in football, and there isn't a number big enough to convince me to take the Jaguars on Sunday.
Pick: Bills 34-13
... It's another unanimous decision.
"The league's top-ranked defense gets a chance to feast on one of the league's lowest-scoring offenses with a less-than-inspiring rookie quarterback who hasn't figured it out yet," O'Donnell said of this matchup. "Hmm. Even if the Bills didn't also have one of the league's best offenses, I'd be willing to lay the points because of Jacksonville's ineptitude. This one shouldn't be close."
Prediction: Bills 34, Jaguars 13
MDS's take: I'm actually surprised the Bills are "only" favored by 14.5 here. They'll blow out the Jaguars.
MDS's pick: Bills 40, Jaguars 12.
Florio's take: By the time this one is over, Urban Meyer may wish he'd gotten fired during the bye week.
Florio's pick: Bills 38, Jaguars 13.
The Bills got off to a slow start against Miami following their bye last week, but that won't happen here. They are too good to let Jacksonville hang around. The Jaguars are a sloppy, poorly-coached team right now. Buffalo is the exact opposite. Josh Allen lights up the Jaguars.
Pick: Bills 34, Jaguars 16
The Bills made things interesting against the Dolphins before kicking it back into high gear for a division rout in Week 8. The Jaguars pleaded no contest early in Seattle with an atrocious performance after a bye. The Bills' defense is a daunting rookie draw for Trevor Lawrence. The Jaguars' pass defense got roasted for big pass plays against top wide receivers in Seattle and Buffalo can present the same problems with Josh Allen's big arm. There should be a strong #BillsMafia contingent to help in #Duval.
Pick: Bills win 34-14