| 2021-10-01 | Next Gen Stats: Allen's Arial Assault Powers Week 3 Win |
| 2021-10-01 | Highmark Community Hero Award: Gwen Mysiak of the P.U.N.T. Pediatric Cancer Collaborative |
| 2021-10-01 | Tremaine Edmunds and Dion Dawkins: "We Know What Time It Is" |
| 2021-10-03 | Coming Soon: Bills vs. Texans |
| 2021-10-03 | Tremaine Edmunds intercepts the Davis Mills pass | Bills vs. Texans |
| 2021-10-03 | Fake QB sneak! Josh Allen bounces outside for 16 yards | Bills vs. Texans |
| 2021-10-03 | Josh Allen eludes rush, hits Stefon Diggs for 31 yards | Bills vs. Texans |
| 2021-10-03 | Micah Hyde intercepts the Davis Mills pass | Bills vs. Texans |
| 2021-10-03 | Josh Allen connects with Stefon Diggs for a 37-yard completion | Bills vs. Texans |
| 2021-10-03 | Bills defeat Texans | Game Highlights | Week 4 |
| 2021-10-03 | Bills' best defensive plays from shutout win | Week 4 |
| 2021-10-03 | Victory Speech: "Another Goose Egg" |
| 2021-10-03 | Cam Lewis: “Trying to Help the Team Win“ |
| 2021-10-03 | Tremaine Edmunds: “Still a Lot of Meat on the Bone“ |
| 2021-10-03 | Mitch Morse: “We Can Be Even More Efficient" |
| 2021-10-03 | Sean McDermott: "Overall Good Team Win" |
| 2021-10-03 | Jaquan Johnson: "Put In A Lot Of Work" |
| 2021-10-04 | Victory Monday: Bills Blank the Texans |
| 2021-10-04 | 2021 Huddle for Hunger Food Drive |
| 2021-10-04 | True View: Cam Lewis Plays Punch Out; Diggs' Great Sideline Grab |
| 2021-10-04 | Leslie Frazier: "It's Going To Be A Challenge" |
| 2021-10-04 | Brian Daboll: “Do Our Job the Best Way We Can Do It” |
| 2021-10-04 | Buffalo Bills Military Recognition: Week 4 |
| 2021-10-04 | Sean McDermott: "Anxious to See Where We Go From Here" |
| 2021-10-05 | Inspire Change Community Organization of the Game: The Bison Children's Scholarship Fund |
| 2021-10-05 | Crucial Catch Pregame Ceremony 2021 |
| 2021-10-05 | Kyle Brandt: "Buffalo Needs This Game More Than Kansas City" |
| 2021-10-05 | Chopping Wood | Bills Shutout the Texans |
| 2021-10-06 | Tremaine Edmunds joins the PFF 90 Club | Week 4 |
| 2021-10-06 | Mic'd Up: Josh Allen |
| 2021-10-06 | PFF: Bills vs Chiefs preview Week 5 |
| 2021-10-06 | Sean McDermott: "Focus On This Game" |
| 2021-10-06 | Tyler Matakevich: "I'm Just So Excited For This Opportunity" |
| 2021-10-06 | Bills at Chiefs | Numbers to know + score predictions | Week 5 |
| 2021-10-06 | Josh Allen: “We Gotta Be On Point” |
| 2021-10-06 | Stefon Diggs: “Continue to Play Good Ball” |
| 2021-10-06 | Dawson Knox: “Keep Stacking Good Days" |
| 2021-10-06 | Tremaine Edmunds: “A Lot of Room to Grow" |
| 2021-10-07 | Kurt Warner's Top QB storylines to watch in Week 5 |
| 2021-10-07 | GMFB | Zack Moss details how Bills are preparing for Chiefs in Week 5 |
| 2021-10-07 | Bills Pod Squad | S2: Ep. 5 | Mike Tirico |
| 2021-10-07 | Emmanuel Sanders: “Trying to Go Out Here and Get a Win” |
| 2021-10-08 | Bills' top plays through quarter mark of 2021 season |
| 2021-10-08 | GMFB | What we're watching for in Bills-Chiefs Week 5 matchup |
| 2021-10-08 | GMFB | Players who will shine in Week 5 |
| 2021-10-08 | Sean McDermott: “There’s No Substitute for Experience” |
| 2021-10-08 | Dion Dawkins: “Every Game is a Big Game in this League” |
| 2021-10-08 | Greg Cosell Previews Bills-Chiefs | One Bills Live |
| 2021-10-09 | Sportsology: ECMC - Jaquan Johnson's 25-Yard Interception Return |
| 2021-10-09 | Bills on Tap: Drake vs. Kanye West |
| 2021-10-10 | Coming Soon: Bills vs. Chiefs |
| 2021-10-11 | Josh Allen rushes for 22 yards | Bills at Chiefs |
| 2021-10-11 | Josh Allen rushes for a 9-yard touchdown | Bills at Chiefs |
| 2021-10-11 | Siran Neal forces a fumble on kickoff coverage | Bills at Chiefs |
| 2021-10-11 | Zack Moss gains 24 yards on this reception | Bills at Chiefs |
| 2021-10-11 | Josh Allen with a 35-yard touchdown pass to Emmanuel Sanders | Bills at Chiefs |
| 2021-10-11 | Josh Allen connects with Stefon Diggs for a 61-yard pass | Bills at Chiefs |
| 2021-10-11 | Dawson Knox with a 53-yard touchdown catch from Josh Allen | Bills at Chiefs |
| 2021-10-11 | Bills defense stops Kansas City on fourth down | Bills at Chiefs |
| 2021-10-11 | Dawson Knox with a spectacular catch for a 41-yard gain | Bills at Chiefs |
| 2021-10-11 | Can't miss play | Micah Hyde with an interception-touchdown | Bills at Chiefs |
| 2021-10-11 | Tip drill! Greg Rousseau intercepts the Patrick Mahomes pass | Bills at Chiefs |
| 2021-10-11 | Emmanuel Sanders connects with Josh Allen for a 9-yard touchdown | Bills at Chiefs |
| 2021-10-11 | Bills dominate Chiefs | Game Highlights | Week 5 |
| 2021-10-11 | Josh Allen's best plays from 4-TD game | Bills at Chiefs | Week 5 |
| 2021-10-11 | Sean McDermott: “Everyone Had a Hand in This” |
| 2021-10-11 | Josh Allen: “We Had a lot of Explosive Plays” |
| 2021-10-11 | GMFB | Where Bills, Chiefs stand after 'SNF' in Week 5 |
| 2021-10-11 | Dawson Knox and Emmanuel Sanders: "Today Was a Big Step" |
| 2021-10-11 | Tremaine Edmunds: “We Had Some Big Takeaways” |
| 2021-10-11 | Jordan Poyer and Micah Hyde: “It’s a Good Road Win For Us” |
| 2021-10-11 | True View: Micah Hyde Pick 6 |
| 2021-10-11 | Sean McDermott: “Players Executed at a High Level” |
| 2021-10-11 | Brian Daboll: “You Have to Be Consistent” |
| 2021-10-11 | Leslie Frazier: "All Did A Terrific Job For Us" |
| 2021-10-11 | Frito-Lay Crunchtime Play: Allen's Hurdle Leads to Bills TD Against Kansas City |
| 2021-10-12 | An unstoppable performance from the Bills | Baldy's Breakdowns |
| 2021-10-12 | Who is the best QB in the NFL right now? 'GMFB' weighs in |
| 2021-10-12 | 'GMFB' selects the defining image of Week 5 |
| 2021-10-12 | Josh Allen's 3 most improbable completions | Week 5 |
| 2021-10-12 | Kyle Brandt: "It Was An Absolute Annihilation" |
| 2021-10-12 | Mic'd Up: Dawson Knox |
| 2021-10-13 | Best Greg Rousseau plays against the Kansas City Chiefs | Week 5 |
| 2021-10-13 | Bills at Titans | Numbers to know + score predictions | Week 6 |
| 2021-10-14 | Beyond Blue & Red | Taron Johnson: Going the Distance |
| 2021-10-14 | Lincoln Loud announces Josh Allen as MVP of Week 5 'NFL Slimetime' |
| 2021-10-14 | Josh Allen tells Dylan Schefter how far he can throw a football | 'NFL Slimetime' |
| 2021-10-14 | Mini-movie | An in-depth look at the Bills' Week 5 victory over the Chiefs |
| 2021-10-14 | Game Preview | Bills at Titans | Week 6 |
| 2021-10-14 | Taron Johnson: "I'm Looking to Score Each Time I Get an Interception" |
| 2021-10-14 | Sean McDermott: “Learn and Grow” |
| 2021-10-14 | Jordan Poyer: "Reset and Refocus" |
| 2021-10-14 | Stefon Diggs: "I'm Not a Big Excuse Guy" |
| 2021-10-14 | Josh Allen: "We Gotta Come Out Ready To Go" |
| 2021-10-14 | Taron Johnson: "I Wanted To Be Here...I Love This Place" |
| 2021-10-15 | Bills' Top 5 plays vs. Titans | NFL Throwback |
| 2021-10-15 | Get your 'BFLO Invasion' Rally Towel today! |
| 2021-10-15 | Greg Cosell Previews Bills-Titans on MNF |
| 2021-10-15 | Micah Hyde: "Bills Mafia Always Travels There Well" |
| 2021-10-15 | Greg Rousseau: "A Lot of Us Are Pretty Versatile" |
| 2021-10-15 | Emmanuel Sanders: "We Got a Great Offensive Coordinator" |
| 2021-10-16 | Total Access | Dawson Knox talks about his breakout season |
| 2021-10-16 | Game Theory | Week 6 win probabilities, score projections |
| 2021-10-16 | Dion Dawkins: "Great Group of Players, That Play Well Together" |
| 2021-10-16 | Tremaine Edmunds: "Still Lot More Work To Be Done" |
| 2021-10-17 | Coming Soon: Bills vs. Titans |
| 2021-10-17 | Bills on Tap: What Would You Name This Dog? |
| 2021-10-18 | Bills at Titans 'MNF' projections | Week 6 | Game Theory |
| 2021-10-19 | Devin Singletary goes Beast Mode on this 14-yard run | Bills at Titans |
| 2021-10-19 | Jordan Poyer intercepts the Ryan Tannehill pass | Bills at Titans |
| 2021-10-19 | Josh Allen with a 14-yard touchdown pass to Stefon Diggs | Bills at Titans |
| 2021-10-19 | Josh Allen with a 29-yard touchdown pass to Cole Beasley | Bills at Titans |
| 2021-10-19 | Tommy Sweeney catches a 1-yard touchdown pass | Bills at Titans |
| 2021-10-19 | CAN'T MISS PLAY | Dawson Knox finds Josh Allen on a two-point conversion | Bills at Titans |
| 2021-10-19 | Can't-Miss Play: Josh Allen's Herculean leap in crunch time is INTENSE | Bills at Titans |
| 2021-10-19 | Can't-Miss Play: Titans' D stops Buffalo with game-winning stop on fourth down | Bills at Titans |
| 2021-10-19 | Titans defeat Bills in Monday Night Thriller | Game Highlights | Week 6 |
| 2021-10-19 | Josh Allen's best plays from 353-yard game | Week 6 |
| 2021-10-19 | Every Stefon Diggs catch from his 89-yard game | Week 6 |
| 2021-10-19 | Bills' top plays from Week 6 | Bills at Titans |
| 2021-10-19 | James Jones: 'I absolutely love' Bills' decision to go for it on fourth down vs. Titans |
| 2021-10-19 | Josh Allen & Cole Beasley: "Game of Inches" |
| 2021-10-19 | Sean McDermott: "We Didn't Get the Job Done" |
| 2021-10-19 | Jordan Poyer & Micah Hyde: "We Trust Our Coaches" |
| 2021-10-19 | Mitch Morse: "Tough Pill to Swallow" |
| 2021-10-19 | Best team in the AFC through Week 6? 'GMFB' weighs in |
| 2021-10-19 | Tremaine Edmunds: "We Just Gotta Be Better" |
| 2021-10-19 | Frito-Lay Crunchtime Play: Dawson Knox Finds Josh Allen for Key Two-Point-Conversion |
| 2021-10-19 | Sean McDermott: “We Will Continue to Improve” |
| 2021-10-20 | Dawson Knox's top plays at the 2021 bye week |
| 2021-10-21 | Buffalo Bills 2021 Flag Football Program presented by M&T Bank |
| 2021-10-21 | Bills on Tap: Haunted House |
| 2021-10-21 | Mic'd Up: Dion Dawkins |
| 2021-10-21 | Mic'd Up: Best of the First 7 Weeks |
| 2021-10-22 | Stefon Diggs' top plays at the 2021 bye week |
| 2021-10-24 | WATCH: Bills Highlights From the First Six Games |
| 2021-10-26 | Kyle Brandt: "Allen Is Gonna Light Them Up" |
| 2021-10-26 | Chopping Wood | Bills Back From The Bye Week |
| 2021-10-27 | 2021 Toyota Rookie Club Virtual Youth Football Clinic |
| 2021-10-27 | Sean McDermott: “I Believe in this Football Team” |
| 2021-10-27 | Bills vs. Dolphins | Numbers to know + score predictions | Week 8 |
| 2021-10-27 | Josh Allen: “We’re Focused on the Task at Hand” |
| 2021-10-27 | Jordan Poyer: “Continue to Get Better” |
| 2021-10-27 | Stefon Diggs: “Everybody Doing Their Part” |
| 2021-10-28 | A tribute to Bills fans | Good luck Pepsi |
| 2021-10-28 | Game Preview | Bills vs. Dolphins | Week 8 |
| 2021-10-28 | Zack Moss: "We're Excited to Finally Get Back" |
| 2021-10-28 | Brian Daboll: "This is a Player's Game" |
| 2021-10-28 | Leslie Frazier: "We'll Have Our Work Cut Out For Us" |
| 2021-10-28 | Micah Hyde: "Sky Is the Limit" |
| 2021-10-28 | Emmanuel Sanders: "We Are Scoring Points" |
| 2021-10-28 | Tommy Sweeney: "I'm Ready, I'm Excited" |
| 2021-10-28 | Next Gen Stats: Defensive Dominance and Success from the Slot |
| 2021-10-29 | Players who will shine in Week 8 'GMFB' |
| 2021-10-29 | Bills Pod Squad | S2 Ep. 7 | Jack Mancuso |
| 2021-10-29 | Tremaine Edmunds and Dion Dawkins Availability |
| 2021-10-29 | Greg Cosell Previews Dolphins-Bills |
| 2021-10-30 | Coming Soon: Bills vs Dolphins |
| 2021-10-31 | Josh Allen rushes for a 34-yard gain | Bills vs. Dolphins |
| 2021-10-31 | Micah Hyde recovers Dolphins' botched snap in red zone | Bills vs. Dolphins |
| 2021-10-31 | Josh Allen with an 8-yard touchdown pass to Gabriel Davis | Bills vs. Dolphins |
| 2021-10-31 | Stefon Diggs catches a 19-yard touchdown from Josh Allen | Bills vs. Dolphins |
| 2021-10-31 | Josh Allen exhibits his power on key 12-yard run | Bills vs. Dolphins |
| 2021-10-31 | Jordan Poyer seals win with interception of Tua Tagovailoa | Bills vs. Dolphins |
| 2021-10-31 | Josh Allen's best plays vs. Miami | Week 8 |
| 2021-10-31 | Buffalo Bills sweep the Miami Dolphins | Game Highlights | Week 8 |
| 2021-10-31 | Victory Speech: "That's The Way To Fight" |
| 2021-10-31 | Jerry Hughes: "We Got Back To Playing Buffalo Bills Football" |
| 2021-10-31 | Tremaine Edmunds: "Everybody Stayed Motivated" |
| 2021-10-31 | Josh Allen and Dion Dawkins Postgame After Win Over Dolphins |
| 2021-10-31 | Sean McDermott: "We Made Adjustments and the Players Executed" |
