| 2019-10-01 | Play 60/Fitness for Kids Kickoff 2019 |
| 2019-10-01 | Power Rankings | Week 5 |
| 2019-10-02 | Sean McDermott: "Our Unit Does A Good Job Of Playing Team Defense" |
| 2019-10-02 | Hollywood Actor William Fichtner Joins One Bills Live |
| 2019-10-02 | Frank Gore: "I'm Just Trying to Play Ball" |
| 2019-10-02 | True View: Hyde Intercepts Brady |
| 2019-10-02 | Bills Minute: Allen Remains in Concussion Protocol |
| 2019-10-03 | Game Preview | Bills vs. Titans | Week 5 |
| 2019-10-03 | John Brown: "He's a Leader" |
| 2019-10-03 | Mitch Morse Joins One Bills Live |
| 2019-10-03 | Jordan Poyer: "We Believe in Ourselves" |
| 2019-10-04 | Coming Soon: Bills at Titans |
| 2019-10-04 | Top 5 Bills Players: PFF Grades at the quarter mark |
| 2019-10-04 | Kim Pegula and the Bills support Safe Sleep Awareness campaign |
| 2019-10-05 | 'NFL 100 Greatest' Games, No. 7: Oilers-Bills in 1992 AFC Wild Card |
| 2019-10-05 | NFL 100 Roundtable: Bruce Smith explains what made him elite |
| 2019-10-06 | Highlight: Trent Murphy stops Derrick Henry in the backfield |
| 2019-10-06 | Highlight: Josh Allen finds Lee Smith wide open for 8-yard TD |
| 2019-10-06 | Highlight: Duke Williams makes catch for Bills first down |
| 2019-10-06 | Highlight: Lorenzo Alexander sacks Mariota |
| 2019-10-06 | Highlight: Bills block Cairo Santos' field-goal attempt in the fourth quarter |
| 2019-10-06 | Highlight: Josh Allen's first down run seals game for Bills |
| 2019-10-06 | Bills vs. Titans highlights | Week 5 |
| 2019-10-06 | Josh Allen: "We Made Some Plays When It Counted" |
| 2019-10-06 | Lorenzo Alexander: "Everybody's Involved In It" |
| 2019-10-07 | Bills Minute: Bills Top the Titans 14-7 |
| 2019-10-07 | Lee Smith: "We have to make the plays and we did tonight" |
| 2019-10-07 | Watch: Head Coach Sean McDermott's Post Game Speech |
| 2019-10-07 | What We Learned: Bills at Titans | Week 5 |
| 2019-10-07 | Lee Smith: “There’s something about him that’s special” |
| 2019-10-07 | Slow-Mo Monday: Bills at Titans |
| 2019-10-07 | Gabe's Collision Impact Player of the Game: Jordan Phillips |
| 2019-10-07 | Do the Bills belong in the conversation with Kansas City Chiefs, New England Patriots? |
| 2019-10-07 | Sean McDermott: "It's At A Good Time For Us To Get Some Rest" |
| 2019-10-08 | Bills History: By the Numbers | Pegula’s Ownership Through the Years |
| 2019-10-09 | Every team's best play | Week 5 |
| 2019-10-13 | Jim Kelly and Josh Allen | Part 2 | Behind the Celly |
| 2019-10-14 | Highlights from the First Five Weeks |
| 2019-10-14 | NFL Network's Deion Sanders: Why the Bills are the Patriots' biggest competition in the AFC |
| 2019-10-14 | Levi Wallace: “I want to keep going out there and competing” |
| 2019-10-14 | Leslie Frazier: "Those Days Off, We Needed Them" |
| 2019-10-14 | Ed Oliver: "I Was Ready To Get Back" |
| 2019-10-14 | Jordan Poyer: "No Team In The NFL That You Can Look Past" |
| 2019-10-14 | Lorenzo Alexander: "It's Been A Pleasure To Play Here" |
| 2019-10-15 | Chopping Wood: Touchdowns and Takedowns |
| 2019-10-16 | Coffee with the Bills: Isaiah McKenzie and Andre Roberts |
| 2019-10-16 | Sean McDermott: "We've got to be disciplined" |
| 2019-10-16 | Jon Feliciano: “I knew I’d fit in with the people in Buffalo” |
| 2019-10-16 | Bills Minute: Back from Bye Week |
| 2019-10-17 | Micah Hyde: "Another Opportunity" |
| 2019-10-17 | Game preview | Bills vs. Dolphins | Week 7 |
| 2019-10-17 | What's the Scoop with Dawson Knox |
| 2019-10-17 | Chill with the Bills: Tre'Davious White's Hockey Trivia |
| 2019-10-17 | Former Bills kicker Steve Christie joins One Bills Live |
| 2019-10-17 | Bills LS Reid Ferguson joins One Bills Live |
| 2019-10-18 | Coming Soon: Bills vs Dolphins |
| 2019-10-18 | My View: Kurt Coleman |
| 2019-10-18 | Family Fun Night 2019 |
| 2019-10-19 | Cynthia's Game Projections for Week 7 |
| 2019-10-20 | One Buffalo Community Award: National Federation for Just Communities |
| 2019-10-20 | Sportsology: ECMC - McKenzie's 46-Yard Jet Sweep |
| 2019-10-20 | Highlight: Bills FB Pat DiMarco turns short throw into huge catch and run |
| 2019-10-20 | Highlight: Ed Oliver records first career sack |
| 2019-10-20 | Highlight: Tre'Davious White gets incredible diving INT |
| 2019-10-20 | Highlight: Josh Allen completes two-point conversion |
| 2019-10-20 | Highlight: Tre'Davious White forces his second turnover |
| 2019-10-20 | Highlight: Josh Allen connects with Cole Beasley for TD |
| 2019-10-20 | Can't-Miss Play: Bills S Micah Hyde returns onside kick for TD |
| 2019-10-20 | Dolphins vs. Bills highlights | Week 7 |
| 2019-10-20 | John Brown: "You Can't Take A Team For Granted" |
| 2019-10-20 | Sean McDermott: "Rally Together" |
| 2019-10-20 | Cole Beasley: "It's a Game of Extremely Highs and Extremely Lows" |
| 2019-10-21 | Bills Minute: Buffalo tops Miami 31-21 |
| 2019-10-21 | Slow-Mo Monday: Bills vs Dolphins |
| 2019-10-21 | Tremaine Edmunds: “I love that crowd” |
| 2019-10-21 | Highlight: Josh Allen Pass to Duke Williams |
| 2019-10-21 | Sean McDermott: "Another Week for Us to Improve" |
| 2019-10-21 | Brian Daboll: "Credit Our Guys for Sticking Together" |
| 2019-10-21 | Leslie Frazier: "Feels Good to be 5-1" |
| 2019-10-22 | Beyond Blue and Red Dion Dawkins: Stir it Up |
| 2019-10-22 | Chopping Wood: Tre White's Takeaways |
| 2019-10-23 | Numbers to know | Eagles vs. Bills preview | Week 8 |
| 2019-10-23 | Jordan Phillips: "It's going to be a big challenge for us” |
| 2019-10-23 | Bills Minute: "He Is Playing at a High Level" |
| 2019-10-23 | Sean McDermott: "Have to Earn It" |
| 2019-10-23 | Josh Allen: "We've Gotta Execute Our Stuff" |
| 2019-10-23 | Tre'Davious White: "I just Want to Win Each and Every rep" |
| 2019-10-23 | Micah Hyde: "Every team is hungry" |
| 2019-10-23 | Lee Smith: "Be Smart and Tough" |
| 2019-10-24 | What's the Scoop with Frank Gore |
| 2019-10-24 | Game Preview | Bills vs. Eagles | Week 8 |
| 2019-10-24 | Isaiah McKenzie: “This is a craft” |
| 2019-10-25 | Coming Soon: Bills vs. Eagles |
| 2019-10-25 | An inside look at the Josh Allen-Oishei Hospital-New Era Cap design project |
| 2019-10-26 | True View: Josh Allen TD pass to Cole Beasley |
| 2019-10-27 | Jim Kelly passes the torch to Bills QB Josh Allen in 'NFL GameDay Morning' interview |
| 2019-10-27 | Highlight: Josh Allen delivers TD to Cole Beasley |
| 2019-10-27 | Highlight: Bills' defense smothers Eagles' trick play |
| 2019-10-27 | Highlight: Josh Allen connects with Tyler Kroft for 20 yards |
| 2019-10-27 | Highlight: Devin Singletary turns Josh Allen's third down throw into elusive TD |
| 2019-10-27 | Highlight: Bills recover after Boston Scott's fumbled punt return |
| 2019-10-27 | Eagles vs. Bills highlights | Week 8 |
| 2019-10-27 | Sean McDermott: "We'll Learn from the Film" |
| 2019-10-27 | Josh Allen: "We Didn't Play to Our Standard" |
| 2019-10-27 | Lorenzo Alexander: "We have to play good, sound football" |
| 2019-10-27 | Mitch Morse: "We've got each other's backs" |
| 2019-10-27 | Tre'Davious White: "We've got to come back strong" |
| 2019-10-27 | Cole Beasley: "We got to be better" |
| 2019-10-27 | Trent Murphy: "They Executed Better" |
| 2019-10-27 | Micah Hyde: "We've got to get these things corrected" |
| 2019-10-27 | Bills Minute: "Get It Corrected and Move Forward" |
| 2019-10-28 | Gabe's Collision Impact Player of the Game: Matt Milano |
| 2019-10-28 | Slow-Mo Monday: Bills vs Eagles |
| 2019-10-28 | Sean McDermott: "Get The Ball In The Hands Of Our Playmakers" |
| 2019-10-28 | Brian Daboll: "Keep Working" |
| 2019-10-28 | Leslie Frazier: "We Will Make the Corrections" |
| 2019-10-29 | Top 10 Bills plays at midway point of 2019 |
| 2019-10-29 | Chopping Wood: Touchdown John Brown |
| 2019-10-30 | Numbers to know | Bills vs. Redskins | Week 9 |
| 2019-10-30 | Micah Hyde: "We Are An Attack Defense" |
| 2019-10-31 | Lorenzo Alexander: "We Know We Have the Talent" |
| 2019-10-31 | Cole Beasley: "Trying to Work to Get Better" |
| 2019-10-31 | Toyota Rookie Club celebrates Halloween at John R. Oishei Children’s Hospital |
